Evidence map›Paper›PMID 40931930›Full record

ArticleJournal of cosmetic dermatology2025

Aesthetic Treatment of the Lips With Hyaluronic Acid Filler: The Multi Vector Lip Technique.

Marcel Vinícius de Aguiar Menezes, Camila Baioni Garcia Dezanetti, Fernanda Waehneldt Pires Penna, Roberta Simão Lopes Cury, Sabrina Bortoletto Gomes de Aquino

Abstract readMulticenter Study
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marcel Vinícius de Aguiar MenezesPrivate Practice in Plastic Surgery and Dermatology, Aracaju, Sergipe, Brazil.
Camila Baioni Garcia DezanettiPrivate Practice in Dermatology, Pato Branco, Paraná, Brazil.
Fernanda Waehneldt Pires PennaPrivate Practice in Dermatology, Rio de Janeiro, Rio de Janeiro, Brazil.
Roberta Simão Lopes CuryPrivate Practice in Dermatology, São Paulo, São Paulo, Brazil.
Sabrina Bortoletto Gomes de AquinoDepartment of Dermatology, University of Taubate (UNITAU), Lorena, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyaluronic acid (HA) fillers are a key treatment in the augmentation and rejuvenation of the lips. The novel Multi Vector (MV) Lip technique has been developed using specific injection vectors in geometric forms to shape the lips-allowing precise customization according to the needs of individual patients.

aimsTo describe the MV Lip technique and evaluate its safety and effectiveness in patients treated across five centers in Brazil.

methodsThis was a retrospective analysis of data from adult female subjects. Eligible patients were treated using the HA filler, VYC-17.5L, in multiple different zones of the lips and perioral area, based on predefined vectors filling geometric shapes.

resultsA total of 253 patients from a range of ethnic backgrounds were included (mean age: 41.0 ± 12.9 years). They received a mean of 1.06 ± 0.21 mL of VYC-17.5L. On a scale from 1 (poor) to 4 (excellent), mean patient satisfaction with the result was 3.92 ± 0.28. Adverse events were minor cases of edema (n = 40; 15.8%) and bruising (n = 28; 11.1%). There were no major complications and no cases of vascular occlusion.

conclusionsThe MV Lip technique offers a safe, effective, and reproducible method that is sufficiently versatile to be used across all types of female lips.

Indexed as

Cosmetic TechniquesDermal FillersHyaluronic AcidLipAdultBrazilEdemaEstheticsFemaleHumansMiddle AgedPatient SatisfactionRejuvenationRetrospective StudiesTreatment OutcomeDermal FillersHyaluronic Acidfillerhyaluronic acidlipvectorVYC‐17.5L

Identifiers

PMID40931930
PMCPMC12424118

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.