In one paragraphArticle in Pediatric transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Syed Ali HusainDepartment of Medicine, Division of Nephrology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.ORCID 0000-0002-1823-0117 Lindsey M MaclayDepartment of Medicine, Division of Nephrology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.ORCID 0009-0007-9875-4087 Miko YuDepartment of Medicine, Division of Nephrology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.ORCID 0000-0001-5491-0278 Sandra AmaralDivision of Nephrology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7357-242X John McAteerDivision of Nephrology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-8913-6219 Vishnu PotluriRenal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3307-8926 Jesse D ScholdDepartment of Surgery, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-5341-7286 Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.ORCID 0000-0002-5305-9685 Funding
Reaching Equity for Adults and CHildren in Transplant (REACH-TRANSPLANT)R01DK120886 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AMARAL, SANDRA, KU, ELAINE · 2019 to 2023
$3.5MContinuous Therapeutic Drug Monitoring of Antibiotics in CRRTR01DK126739 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOHAN, SUMIT · 2021 to 2024
$2.8MIndia - Factors of CKDu in Uddanam Study (India-FOCUS)U01DK130058 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Vivekanand Jha, Sumit Mohan · 2021 to 2026
$2.6M5/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical CenterU01DK116066 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sumit Mohan, Deirdre Sawinski · 2017 to 2026
$2.5MIdentifying and exploring solutions to the ethical challenges of ApoL1 testing of donors with recent African ancestry through mixed methods research with stakeholdersR01MD014161 · NIMHD · WASHINGTON UNIVERSITY · PI DUBOIS, JAMES M, MOHAN, SUMIT · 2019 to 2021
$1.2MIncreasing Minority Population Awareness through Community Teaching for Improved Organ Donation (IMPACT for Improved Organ Donation)R01DK114893 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOHAN, SUMIT · 2017 to 2021
$1.2MUsing Decision Making Science to Optimize Deceased Donor Kidney AllocationK23DK133729 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUSAIN, SYED ALI · 2022 to 2025
$678kPromoting Diversity and Sustainability in the NIDDK-Supported Research Workforce through Mentoring Early Career Investigators: Focus on Health EquityK26DK138377 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI Sandra Amaral · 2023 to 2026
$478kHennepin Healthcare Research InstituteNIDDK NIH HHS K23 DK133729NIDDK NIH HHS K23DK133729NIDDK NIH HHS K26 DK138377NIDDK NIH HHS R01 DK114893NIDDK NIH HHS R01 DK120886NIDDK NIH HHS R01 DK126739NIDDK NIH HHS U01 DK116066NIDDK NIH HHS U01 DK130058NIMHD NIH HHS R01 MD014161
6 · The paper itselfAbstract
backgroundChanges to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric-prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.
methodsWe identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.
resultsAmong 3202 candidates included in the analysis, 124 (4%) consented to receive HCV+ deceased donor kidney offers, and 3077 (96%) did not. In adjusted logistic regression, higher candidate age (OR 1.09 per year, 95% CI 1.03-1.15, p = 0.002) and high PRA status (OR 2.76, 95% CI 1.42-5.37, p = 0.003) were associated with a higher odds of consenting to receive HCV+ donor offers, whereas Hispanic ethnicity was associated with lower odds (OR 0.44, 95% CI 0.28-0.72, p = 0.001) of consenting to receive these offers. 2773 candidates (87%) received a transplant. There was no significant association between HCV+ donor offer consent status and transplant rate after adjusting for candidate characteristics. Only 1 received a kidney from a HCV+ donor.
conclusionsConsent to receive HCV+ donor kidney offers was rare among pediatric kidney transplant candidates. Allocation changes that increase the proportion of pediatric-prioritized kidneys that are HCV+ may decrease access to transplant for pediatric candidates.
Indexed as
Donor SelectionHepatitis CInformed ConsentKidney Failure, ChronicKidney TransplantationTissue and Organ ProcurementTissue DonorsAdolescentChildChild, PreschoolFemaleHumansInfantLogistic ModelsMaleRetrospective Studiesallocationdeceased donorhepatitis Ckidney transplantationpediatricswaitlist
Identifiers
PMID40931645
PMCPMC12558682
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