Evidence map›Paper›PMID 40931632›Full record

ArticleThe Journal of clinical investigation2025

Welsh, González, and Negulescu share Lasker Award recognizing transformative treatments for people with cystic fibrosis.

Benjamin D Singer, G R Scott Budinger

Abstract read
In one paragraph

Article in The Journal of clinical investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Benjamin D SingerDivision of Pulmonary and Critical Care Medicine, and.
G R Scott BudingerDivision of Pulmonary and Critical Care Medicine, and.

Funding

Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GR Scott Budinger · 2015 to 2026
$26.9M
Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
The Neu-Lung Consortium: Neutrophilic Mechanisms of Inflammation, Injury, and Repair in Lung and Airways DiseasesU19AI181102 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Stephanie Caroline Eisenbarth, Alexander Misharin · 2024 to 2026
$9.3M
Pathogenesis of lung injury mediated by lung-restricted antibodiesR01HL147290 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Ankit Bharat, GR Scott Budinger · 2019 to 2026
$5.2M
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaR01HL149883 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Benjamin David Singer · 2020 to 2026
$4.1M
Targeting abnormal alveolar immune activation and failed epithelial repair in COVID-19R01HL158139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BUDINGER, GR SCOTT, MISHARIN, ALEXANDER · 2022 to 2025
$2.9M
Microglia mediate cognitive dysfunction in elderly survivors of pneumoniaR21AG075423 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BUDINGER, GR SCOTT, MISHARIN, ALEXANDER · 2022 to 2022
$440k
Epigenetic modifiers of regulatory T cell function following viral pneumoniaR01HL153122 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2021 to 2021
$63k
CSRD VA I01 CX001777NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL147290NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NHLBI NIH HHS R01 HL158139NIAID NIH HHS U19 AI135964NIAID NIH HHS U19 AI181102NIA NIH HHS P01 AG049665NIA NIH HHS R21 AG075423
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40931632
PMCPMC12490197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.