ReviewInfluenza and other respiratory viruses2025
Host Immune Response to Respiratory Syncytial Virus Infection in Children.
Review in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Differential antiviral effects and immune responses in nasal and airway organoid during RSV infection: implications for interferon therapy.Frontiers in immunology · 2026Article
- Review
- Host Immune Response to Respiratory Syncytial Virus Infection in Children.Influenza and other respiratory viruses · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Respiratory syncytial virus (RSV) is one of the leading causes of severe respiratory diseases in children, especially in infants. The immune responses induced by RSV infection are a fairly complex process that can contribute significantly to disease severity. Despite decades of research on RSV, many immune mechanisms remain to be explored. A full exploration of these immune responses can contribute to the discovery of new therapeutic and prophylactic approaches. Despite significant advancements in vaccine development and monoclonal antibody research, effective therapeutic options remain limited. This review focuses on how the immune system reacts when children contract the respiratory syncytial virus. We describe the biological characteristics of RSV, viral-cell interactions, immune evasion, innate immunity (including pattern recognition receptors and inflammatory cells), and adaptive immunity (including CD4+ and CD8+ T cells and humoral immune response). Understanding the complicated immune response to RSV infection is essential for developing effective interventions and vaccine developments. This review aims to deepen the understanding of the impact of Respiratory Syncytial Virus (RSV) on the immune system and to contribute to the advancement of practical therapeutic strategies.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.