ArticleJournal of separation science2025
Chlorophylls and β-carotene in Spirulina platensis Dietary Supplements: Nano Liquid Chromatography Versus Diffuse Reflectance Spectroscopy for Establishing Composition, Quality Control, and Comparison of Commercial Products.
Article in Journal of separation science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spirulina is considered a superfood due to its chlorophylls. Two new methods for the determination of chlorophylls and β-carotene were developed here, one based on in-tube solid-phase microextraction (IT-SPME) coupled online to nanoliquid chromatography (nanoLC) with diode array detection (DAD), and the other on ultraviolet-visible diffuse reflectance spectroscopy (UV-vis DRS). A protocol to extract the pigments from spirulina was proposed using ethanol (1.5 mL). The aim is to provide fast and environmentally friendly techniques for both the extraction and measurement of pigments, generating little waste and low energy expenditure. IT-SPME-nanoLC-DAD and UV-vis DRS showed good linearity up to 300 or 600 µg/L and 50 mg/L, with instrumental detection limits between 10 and 50 µg/L and 2 and 5 mg/L, respectively. The % intraday and interday relative standard deviation were between 2 and 9. The HEXAGON tool is used for assessing greenness and sustainability for three scenarios: establishing composition, quality control, and comparison of seven dietary supplements.
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