ArticleNeotropical entomology2025
Larvicidal Effects of Nanoliposomes Containing p-Cresol and Myristica fragrans Houtt. Essential Oil Against Aedes aegypti and Aedes albopictus Mosquitoes.
Article in Neotropical entomology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The control of dengue vector mosquitoes by utilizing plant-based eco-friendly larvicides is pivotal in suppressing the spread of dengue with minimum environmental toxicity. This study aimed to evaluate the larvicidal activity of nanoliposomes containing p-cresol and Myristica fragrans Houtt. essential oil (EO) against Aedes aegypti L. and Aedes albopictus (Skuse, 1894) larvae. The constituents of extracted EO were assessed by GC-MS analyses. The in vitro and in silico inhibitory activities of p-cresol and M. fragrans EO against acetylcholinesterase and α-amylase enzymes of Larvae were assessed. Nanoliposomes were prepared and characterized and their Larvicidal activities were analyzed against 4th instar Aedes larvae. Major constituents identified from EO were α-pinene, sabinene, β-pinene, β-phellandrene, γ-terpinene, isopulegol, and myristicin. The results showed that both p-cresol and M. fragrans EO possess significant inhibitory activity against α-amylase. Moreover, M. fragrans EO also inhibited the activity of acetylcholinesterase enzyme. The molecular docking results also confirmed these inhibitory activities. Myristica fragrans EO and p-cresol as well as their nanoliposomes showed significant larvicidal activities against Ae. aegypti and Ae. albopictus. The LC
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