Evidence map›Paper›PMID 40931255›Full record

ArticleJournal of general internal medicine2026

Factors Associated with Loneliness Among Older Adults Who Experienced Homelessness: Results from the HOPE HOME Study.

Yeqing Yuan, Jennifer L Evans, Torsten B Neilands, Karen Valle, Cheyenne M Garcia, Margot B Kushel

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yeqing YuanUCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA.
Jennifer L EvansUCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA.
Torsten B NeilandsUCSF Division of Prevention Science, Department of Medicine, University of California, San Francisco, CA, USA.
Karen ValleUCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA.
Cheyenne M GarciaUCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA.
Margot B KushelUCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA. margot.kushel@ucsf.edu.ORCID 0000-0002-1361-6889

Funding

RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Torsten Brian Neilands · 1997 to 2026
$19.5M
Mentoring Researchers in Aging in Vulnerable PopulationsK24AG046372 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUSHEL, MARGOT B · 2015 to 2025
$1.9M
National Institute of Aging R01AG041860NIA NIH HHS K24AG046372NIA NIH HHS P30 AG015272
6 · The paper itself

Abstract

backgroundOlder homeless-experienced adults are at higher risk of loneliness than general older adults. Loneliness is associated with multiple adverse health and mental health outcomes. Less is known about factors contributing to loneliness among older adults who experience homelessness. This study aims to examine the relationship between relevant factors and loneliness.

methodsWe used data collected from January 2015 to February 2023 from the Health Outcomes in People Experiencing Homelessness in Older Middle agE (HOPE HOME) study, an ongoing longitudinal cohort study of older adults, homeless at study entry, conducted in Oakland, CA. We used structural equation modeling (SEM) to investigate the relationships between trauma, mental health status, physical health and functional status, housing factors, social support, and substance use and loneliness.

resultsOur analytic sample consisted of 385 participants who completed 2099 assessments. The majority of participants were men (74.8%), Black (82.1%), and not partnered (87.5%). At the first loneliness interview, 41.8% remained homeless, and 39.2% met the criteria for loneliness. Poor mental health and a lack of social support were associated with loneliness. Poor physical health and functional status had an indirect effect on increased loneliness through worsening mental health status. Experiences of trauma had an indirect effect on increased loneliness through worsening mental health status. The Shelter-In-Place mandate was associated with decreased loneliness. We found no association between regaining housing and decreased loneliness.

conclusionIn a longitudinal study of older adults, homeless at study entry, we found that mental health had direct impacts on loneliness, and other factors (i.e., trauma, physical health, and functional status) contributed to increased loneliness through their negative effects on mental health. Regaining housing was not associated with a decrease in loneliness. These findings highlight the need for interventions beyond housing, including mental healthcare, trauma-informed support, and social engagement opportunities.

Indexed as

Ill-Housed PersonsLonelinessAgedCohort StudiesFemaleHealth StatusHumansLongitudinal StudiesMaleMental HealthMiddle AgedSocial Supporthomelessnesshousinglonelinessolder adults

Identifiers

PMID40931255
PMCPMC13009309

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.