Evidence map›Paper›PMID 40931140›Full record

ArticleAnalytical and bioanalytical chemistry2025

Development of smartphone-based AIE fluorescence-quenching immunochromatographic sensors for the detection of illicit drugs in various complex sample matrices.

Lijiao Liu, Guanbo He, Lifang Ye, Yong He, Tao Xu, Xiaoli Zhang, Chenxing Zeng, Qifang Song, Jiajie Liang, Yong Tang

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lijiao Liu *GuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Guanbo He *Guangdong Zhongxin Biotech Limited, Guangzhou, 510000, China.
Lifang YeGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Yong HeGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Tao XuGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Xiaoli ZhangGuangdong Zhongxin Biotech Limited, Guangzhou, 510000, China.
Chenxing ZengGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Qifang SongGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Jiajie LiangGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. 631101522@qq.com.
Yong TangGuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. tyjaq7926@163.com.ORCID http://orcid.org/0000-0002-9954-4563

Funding

Guangzhou Science and Technology Program 2025B01J0005the Fundamental Research Funds for the Central Universities 21625329Young Talents Support Program - Seedling Cultivation Program (Class C) at the College of Life Science and Technology, Jinan University 2025-010C
6 · The paper itself

Abstract

Illicit drug abuse poses a significant global threat to public health and social security, highlighting the urgent need for rapid, sensitive, and versatile detection technologies. To address the limitations of traditional chromatographic techniques-such as high costs and slow response times-and the drawbacks of conventional immunochromatographic sensors (ICS), including low sensitivity and non-intuitive signal outputs, a fluorescence-quenching ICS (FQICS) was developed. This sensor leverages fluorescence resonance energy transfer (FRET) between aggregation-induced emission fluorescent microspheres (AIEFMs) and gold nanoparticles (AuNPs). The ICS operates on a positive signal-readout mechanism and is integrated with a smartphone-based portable reader, enabling rapid quantitative detection of methamphetamine (MET), morphine (MOR), and ketamine (KET). Detection limits of 0.041, 0.072, and 0.059 ng mL

Indexed as

Chromatography, AffinityFluorescence Resonance Energy TransferIllicit DrugsSmartphoneSubstance Abuse DetectionFluorescenceGoldHumansLimit of DetectionMetal NanoparticlesMethamphetamineGoldIllicit DrugsMethamphetamineAggregation-induced emissionComplex sample matricesFluorescence-quenchingIllicit drugsImmunochromatographic sensor

Identifiers

PMID40931140

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.