Evidence map›Paper›PMID 40931019›Full record

ArticleLight, science & applications2025

In-line multi-wavelength non-destructive pharma quality monitoring with ultrabroadband carbon nanotubes photo-thermoelectric imaging scanners.

Miki Kubota, Yuya Kinoshita, Sayaka Hirokawa, Daiki Shikichi, Noa Izumi, Naoko Hagiwara, Daiki Sakai, Yuto Matsuzaki, Minami Yamamoto, Leo Takai and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Light, science & applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Miki Kubota *Department of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Yuya Kinoshita *Department of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Sayaka HirokawaDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Daiki ShikichiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Noa IzumiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Naoko HagiwaraDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Daiki SakaiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Yuto MatsuzakiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Minami YamamotoDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Leo TakaiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Yukito KonDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Yuto AoshimaDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Raito OtaDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Mitsuki KosakaDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
Meiling SunLaboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8552, Japan.
Yukio KawanoDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan. kawano@elect.chuo-u.ac.jp.
Kou LiDepartment of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan. li@elect.chuo-u.ac.jp.ORCID http://orcid.org/0000-0001-8756-819X

Funding

MEXT | Japan Science and Technology Agency (JST) ACT-X (JPMJAX23KL)MEXT | Japan Science and Technology Agency (JST) Mirai Program (JPMJMI23G1)MEXT | Japan Society for the Promotion of Science (JSPS) JP22H01553MEXT | Japan Society for the Promotion of Science (JSPS) JP22H01555MEXT | Japan Society for the Promotion of Science (JSPS) JP23H00169MEXT | Japan Society for the Promotion of Science (JSPS) JP23K19125MEXT | Japan Society for the Promotion of Science (JSPS) JP24K01288MEXT | Japan Society for the Promotion of Science (JSPS) JP24K17325MEXT | Japan Society for the Promotion of Science (JSPS) JP25H02154
6 · The paper itself

Abstract

While non-destructive in-line monitoring at manufacturing sites is essential for safe distribution cycles of pharmaceuticals, efforts are still insufficient to develop analytical systems for detailed dynamic visualisation of foreign substances and material composition in target pills. Although spectroscopies, expected towards pharma testing, have faced technical challenges in in-line setups for bulky equipment housing, this work demonstrates compact dynamic photo-monitoring systems by selectively extracting informative irradiation-wavelengths from comprehensive optical references of target pills. This work develops a non-destructive in-line dynamic inspection system for pharma agent pills with carbon nanotube (CNT) photo-thermoelectric imagers and the associated ultrabroadband sub-terahertz (THz)-infrared (IR) multi-wavelength monitoring. The CNT imager in the proposed system functions in ultrabroadband regions over existing sensors, facilitating multi-wavelength photo-monitoring against external sub-THz-IR-irradiation. Under recent advances in the investigation of functional optical materials (e.g., gallium arsenide, vanadium oxide, graphene, polymers, transition metal dichalcogenides), CNTs play advantageous leading roles in collectively satisfying informative efficient photo-absorption and solution-processable configurations for printable device fabrication into freely attachable thin-film imagers in pharma monitoring sites. The above non-destructive dynamic monitoring system maintains in-line experimental setups by integrating the functional thin-film imager sheets and compact multiple photo-sources. Furthermore, permeable sub-THz-IR-irradiation, which provides different transmittance values specific to non-metallic materials per wavelength or composition, identifies constituent materials for pharma agents themselves and concealed foreign substances in a non-contact manner. This work finally inspects invisible detailed features of pharma pills with the non-destructive in-line dynamic photo-monitoring system by incorporating performances of CNT imagers and compact optical setups.

Identifiers

PMID40931019
PMCPMC12423311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.