ArticleBritish journal of anaesthesia2025
Photoacoustic detection of propofol in breath gas for monitoring depth of anaesthesia: from bench to bedside.
Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The trial behind it
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Who cites it
1 citing paper in PubMed.
- Propofol is in the air: can exhaled gas monitoring illuminate intravenous dosing?British journal of anaesthesia · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnsuring adequate depth of i.v. anaesthesia by measuring propofol in breath gas could increase patient safety. Mass spectrometry, representing the reference standard of propofol breath gas measurements, is not feasible in routine clinical practice; hence, a photoacoustic sensor was developed.
methodsThe photoacoustic sensor quantifies propofol concentration in gas via the sound waves emitted by propofol molecules excited by light of specific wavelength and frequency. We studied the performance of the new sensor in propofol test gas, gas sampling bags filled with breath gas from different patients, and performed real-time measurements in patients undergoing propofol anaesthesia in comparison to ion-molecule reaction mass spectrometry.
resultsIn test gas, photoacoustic and mass spectrometry correlated with an R
conclusionsPhotoacoustic measurement of propofol concentration in breath gas is feasible with high accuracy in clinical applications.
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