Evidence map›Paper›PMID 40930839›Full record

ArticleLife science alliance2025

Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions.

Christopher J Vavricka, Masao Mochizuki, Satoshi Yuzawa, Masahiro Murata, Takanobu Yoshida, Naoki Watanabe, Masahiko Nakatsui, Jun Ishii, Kiyotaka Y Hara, Hal S Alper and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christopher J VavrickaDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Japan.ORCID 0000-0003-2101-4359
Masao MochizukiBacchus Bio Innovation, Kobe, Japan.
Satoshi YuzawaDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Japan.
Masahiro MurataGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan.
Takanobu YoshidaGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan.
Naoki WatanabeGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan.
Masahiko NakatsuiAI Systems Medicine Research and Training Center, Yamaguchi University, Yamaguchi, Japan.
Jun IshiiGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan.
Kiyotaka Y HaraDepartment of Environmental and Life Sciences, University of Shizuoka, Shizuoka, Japan.
Hal S AlperCockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Tomohisa HasunumaGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan hasunuma@port.kobe-u.ac.jp.ORCID 0000-0002-8382-2362
Akihiko KondoBacchus Bio Innovation, Kobe, Japan akondo@kobe-u.ac.jp.ORCID 0000-0003-1527-5288
Michihiro ArakiGraduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan maraki@fc.ritsumei.ac.jp.ORCID 0000-0002-6686-4018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass-based fingerprinting can characterize microorganisms; however, expansion of these methods to predict specific gene functions is lacking. Therefore, mass fingerprinting was developed to functionally profile a yeast knockout library. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) fingerprints of 3,238

Indexed as

Gene OntologySaccharomyces cerevisiaeAlgorithmsComputational BiologyGene Knockout TechniquesGenome, FungalMachine LearningMetabolomicsSaccharomyces cerevisiae ProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSupport Vector MachineSaccharomyces cerevisiae Proteins

Identifiers

PMID40930839
PMCPMC12423557

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.