Evidence map›Paper›PMID 40930727›Full record

ArticleJournal of neurointerventional surgery2026

Educational value of remote live-streamed training in endovascular thrombectomy: dose-response and mediation analysis.

Shujuan Gan, Jinfeng Miao, Zhiting Chen, Yan-Min Wu, Huaizhang Shi, Changming Wen, Ming-Zhu Huang, Jintao Chen, Jianhua Guan, Bingbo Zhuang and 7 more

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shujuan GanDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.ORCID http://orcid.org/0009-0003-4149-1635
Jinfeng MiaoDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Zhiting ChenDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Yan-Min WuCerebrovascular and Neuro-Intervention Department, Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China.
Huaizhang ShiNeurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.ORCID http://orcid.org/0009-0007-3338-0037
Changming WenDepartment of Neurology, Nanyang Central Hospital, Nanyang, Henan, China.
Ming-Zhu HuangDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Jintao ChenDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Jianhua GuanDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Bingbo ZhuangDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Hanrong DongDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Ruihan ZhuDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Yuanxiao LiDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Min ZhangDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Jianmin LiuNeurovascular Center, Trauma Center, Naval Medical University Changhai Hospital, Shanghai, China siyuyufen@163.com liu118@vip.163.com doctorwwenhuo@126.com.
Wen-Huo ChenDepartment of Cerebrovascular Disease, Fujian Medical University Union Hospital, Fuzhou, Fujian, China siyuyufen@163.com liu118@vip.163.com doctorwwenhuo@126.com.
Tingyu YiCerebrovascular and Neuro-Intervention Department, Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China siyuyufen@163.com liu118@vip.163.com doctorwwenhuo@126.com.ORCID http://orcid.org/0000-0003-3110-5844

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRemote live-streamed training in endovascular thrombectomy (EVT) is a novel educational strategy. This study evaluated the dose-response relationship between training duration and clinical outcomes, and explored mediation pathways.

methodsIn a prospective cohort study, 1046 participants received remote EVT training, with 1010 completing follow-up. Locally Estimated Scatterplot Smoothing (LOESS) and segmented regression identified training thresholds. Participants were categorized into low (<25 hours), medium (25-70 hours), and high (>70 hours) training groups. Inverse probability of treatment weighting (IPTW) was adjusted for baseline differences. Mediation analysis examined the mechanisms of effect.

resultsA dose-response relationship was evident: outcome improvements accelerated after 25 hours and plateaued beyond 70 hours. After IPTW, patients treated by both medium and high training groups achieved significantly better 90-day outcomes compared with the low training group (medium vs low, adjusted β=1.54, 95% CI 0.94 to 2.15; high vs low, β=3.16, 95% CI 2.28 to 4.04, both P<0.001). Mediation analysis revealed that increased professional competency (25.0%), reduced recanalization time (32.8%), and higher recanalization rates (46.1%) partially explained the improved outcomes (all P<0.001). Sensitivity analyses supported these findings.

conclusionRemote live-streamed EVT training is significantly associated with improved 90-day functional outcomes. The greatest benefits were observed after 25 hours of training and diminishing returns beyond 70 hours. These gains are partly mediated by enhanced professional competency and improved recanalization outcomes, highlighting the importance of structured, high-quality remote training programs for optimizing neurointerventional care.

Indexed as

Endovascular ProceduresStrokeThrombectomyAgedCohort StudiesFemaleHumansMaleMediation AnalysisProspective StudiesTreatment OutcomeInterventionStrokeThrombectomy

Identifiers

PMID40930727
PMCPMC13479681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.