ArticlePerfusion2026
Towards goal-directed perfusion - Part I: Developing physiology-inspired mathematical framework using high-resolution paediatric CPB data.
Article in Perfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundDuring cardiopulmonary bypass (CPB), goal-directed perfusion (GDP) seeks to match oxygen delivery to metabolic demand, but the dynamics of oxygen extraction and intraoperative oxygen demand remain poorly understood, especially in paediatric populations. Existing models rely on limited data and assume, for example, a linear relationship between log oxygen demand and temperature.MethodsWe developed GARIX (Global AutoRegressive Integrated model with eXogenous variables and an equilibrium force) to predict minute-by-minute changes in oxygen extraction ratio (OER) using high-resolution intraoperative data. GARIX combines: (1) an autoregressive term group (ATG) encoding memory of past OER; (2) an exogenous term group (XTG) incorporating recent and planned changes in cardiac index (CI), haemoglobin (Hb), SaO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.