Evidence map›Paper›PMID 40930345›Full record

ArticleJournal of advanced research2026

Multifunctional antifreeze gelatin-based ionic conductive organohydrogel coupled with electrical stimulation for monitoring and accelerated wound healing.

Lantao Wang, Zhengfeng Lu, Qingxin Wu, Shuting Peng, Zhengxiao Wang, Wenxiu Chen, Xiaofei Qin

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Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lantao Wang(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Zhengfeng Lu(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Qingxin Wu(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Shuting Peng(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Zhengxiao Wang(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Wenxiu ChenDepartment of Clinical Medicine, The Fifth Clinical Institution, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China.
Xiaofei Qin(1)School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519000, China. Electronic address: qxf2019300426@zmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTraditional hydrogels with poor mechanical properties and lack of biological activities severely limit their application in wound therapy. Designing multifunctional hydrogels for monitoring and accelerating wound healing remains imperative.

objectivesThe aim of this study is to develop a multifunctional antifreeze ionic conductive Gel-TBA@organohydrogel with antibacterial, anti-inflammatory and antioxidant properties for monitoring and wound treatment.

methodsThe Gel-TBA@organohydrogel were developed through simply adding 2,3,4-trihydroxybenzaldehyde (TBA) into the gelatin (Gel) solution, and further immersed in water/glycerol binary solvent containing ZnSO

resultsAssisted by TBA addition and binary solvent immersion, Gel-TBA@organohydrogel not only exhibits significant antibacterial and ROS scavenging capabilities, but also has commendable mechanical properties (tensile strain: 346 %, toughness: 1.54 MJ/m

conclusionThe Gel-TBA@organohydrogel holds promise for applications in sensing and wound healing, wherein it shows multifunctional abilities and can detect wound exudates and motion behavior, thereby enabling the effective wound care management.

Indexed as

GelatinHydrogelsWound HealingAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBiocompatible MaterialsElectric ConductivityElectric StimulationHumansAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBiocompatible MaterialsGelatinHydrogelsAnti-freezingHofmeister effectIonic organohydrogelMonitoringMultifunctionalWound healing

Identifiers

PMID40930345
PMCPMC13227284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.