Evidence map›Paper›PMID 40930316›Full record

ArticleContemporary clinical trials2025

Testing the efficacy and mechanisms of an SMS intervention focused on motivating peer network support to reduce alcohol consumption in non-collegiate young adults: Protocol for a randomized trial.

Brian Suffoletto, Michael Mason, Christine M Lee, Haley Hedlin

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian SuffolettoDepartment of Emergency Medicine, Stanford University, United States of America. Electronic address: suffbp@stanford.edu.
Michael MasonCenter for Behavioral Health Research, College of Social Work, University of Tennessee, United States of America.
Christine M LeeDepartment of Psychiatry and Behavioral Sciences, University of Washington, United States of America.
Haley HedlinQuantitative Sciences Unit, Stanford School of Medicine, United States of America.

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Stanford Center for Clinical and Translational Research and EducationUM1TR004921 · NCATS · STANFORD UNIVERSITY · PI MANISHA DESAI, DEAN W FELSHER · 2024 to 2026
$30.1M
ASPIRE to Change: Leveraging Text Messaging Peer Support Coaching to Mitigate Hazardous Alcohol Consumption in Non-Collegiate Young AdultsR01AA030986 · NIAAA · STANFORD UNIVERSITY · PI Brian P Suffoletto · 2024 to 2026
$1.9M
NCATS NIH HHS UL1 TR003142NCATS NIH HHS UM1 TR004921NIAAA NIH HHS R01 AA030986
6 · The paper itself

Abstract

backgroundNon-collegiate young adults engage in high rates of heavy drinking but are less likely to access alcohol-related counseling or treatment. Peers play a significant role in shaping drinking behavior, yet few interventions target close peer influence in this population.

methodsThis two-arm randomized controlled trial will enroll 300 young adults aged 18-25 who report 2+ heavy drinking days (HDD; defined as 4+ drinks for a woman and 5+ drinks for a man) in the past 30 days and are not enrolled in college. Participants are randomized (1:1) to receive either (1) an SMS intervention focused on self-monitoring and goal-related strategies (i.e. Commitment-based Binge drinking prevention Intervention: CBI) or (2) ASPIRE, which adds feedback on peer influences and encouragement for positive support. Outcomes are assessed via REDCap-administered surveys at baseline, 3, 6, and 12 months. Additional data include twice-weekly SMS assessments during the 3-month intervention period and GPS-based mobility tracking with simultaneous ecological momentary assessment (EMA) during 7-day windows following each assessment time point. The primary outcome is number of heavy drinking days (HDD) in the past 30 days. Mediation analyses will assess cognitive, social, and environmental mechanisms of change using multilevel structural equation modeling. DISCUSSION: This trial advances the science of digital interventions for alcohol harm reduction in a high-risk and underserved population. ASPIRE is among the first interventions to integrate encouragement for positive peer network support into a scalable mobile platform. The use of high-frequency behavioral and geolocation data allows for novel insights into mechanisms of change.

Indexed as

Alcohol DrinkingBinge DrinkingMotivationPeer GroupText MessagingAdolescentAdultEcological Momentary AssessmentFemaleHumansMalePeer InfluenceRandomized Controlled Trials as TopicSocial SupportYoung AdultAlcohol usePeer influenceYoung adult

Identifiers

PMID40930316
PMCPMC12469887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.