Evidence map›Paper›PMID 40930079›Full record

ArticleJMIR pediatrics and parenting2025

Sex Differences in the Joint Trajectories of Depressive Symptoms and Body Mass Index From Adolescence to Early Adulthood: Longitudinal Observational Study.

Jing Chen, Rui Shan, Wen Yuan, Qiong Wu, Yang Yang, Yi-Hang Yang, Jing-Yao Liu, Wu-Cai Xiao, Shanghang Zhang, Li-Ming Wen and 3 more

Erratum issuedAbstract read
In one paragraph

Article in JMIR pediatrics and parenting, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Jing ChenDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0000-0002-6640-7140
Rui ShanDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0009-0006-7603-337X
Wen YuanInstitute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China.ORCID http://orcid.org/0000-0001-5462-6672
Qiong WuInstitute of Social Science Survey, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-7279-1169
Yang YangDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0009-0006-8429-9573
Yi-Hang YangDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0009-0002-3926-8226
Jing-Yao LiuDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0009-0003-1032-9221
Wu-Cai XiaoDepartment of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0009-0002-7949-1297
Shanghang ZhangThe School of Computer Science, Peking University, Beijing, China.ORCID http://orcid.org/0000-0003-4047-3526
Li-Ming WenSchool of Public Health, The Faculty of Medicine and Health, University of Sydney, Sydney, Australia.ORCID http://orcid.org/0000-0003-1381-4022
Xiao-Rui Zhang *Department of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0000-0002-7030-6529
Zheng Liu *Department of Maternal and Child Health, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China, 86 01082801222 ext 109.ORCID http://orcid.org/0000-0002-0405-2348
Yi SongInstitute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China.ORCID http://orcid.org/0000-0001-6990-6781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adolescence is a critical transitional period between childhood and adulthood, marked by dramatic changes in physical and psychosocial health. Adolescents are vulnerable to both depression and adiposity, but how these conditions evolve over time from adolescence to early adulthood and whether sex differences exist remains unclear. Objective: This study aims to first identify the population heterogeneity in the joint trajectories of depressive symptoms and BMI from adolescence to early adulthood and then explore the sex differences in the joint trajectories. Methods: In this study, we adopt the latent class trajectory modeling to identify the combined trajectories of depressive symptoms and BMI from adolescence at baseline to early adulthood at follow-ups using a longitudinal study (2010-2020). We used the multinomial logistic regressions to examine the sex-specific associations with the trajectory classifications. Results: Our results found that individuals' depressive symptoms and BMI might not always change parallelly from adolescence to early adulthood. Instead, some individuals appeared to be prone to depressive symptoms or elevated BMI, while others were multimorbid with both of them. Moreover, our study identified a clear sex-specific pattern in the joint trajectories of depressive symptoms and BMI: the females were at a higher risk of developing depressive symptoms but remained relatively stable weight status over time (odds ratio [OR] 0.68, 95% CI 0.52-0.89), while the males were at a lower risk of developing depressive symptoms but with an increasing risk of developing adiposity over time (OR 1.83, 95% CI 1.35-2.49). Conclusions: Depressive symptoms and BMI might not always change in parallel from adolescence to early adulthood, and there is a clear sex-specific pattern in the joint trajectories of depressive symptoms and BMI. This will inform the design of future sex-specific interventions that match the distinguished profiles in male and female participants during the period of adolescence and early adulthood, respectively, thus maximizing the intervention effects in preventing both depression and adiposity in early life.

Indexed as

body mass indexdepressive symptomsheterogeneitysextrajectory

Identifiers

PMID40930079
PMCPMC12422740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.