Evidence map›Paper›PMID 40929634›Full record

Observational studyThe New England journal of medicine2025

Medications for Opioid Use Disorder in County Jails - Outcomes after Release.

Peter D Friedmann, Donna Wilson, Thomas J Stopka, Dana Bernson, Ekaterina Pivovarova, Warren Ferguson, Randall A Hoskinson, Rebecca E Rottapel, Benjamin Bovell-Ammon, Ayorkor Gaba and 5 more

Abstract readObservational Study
In one paragraph

Observational study in The New England journal of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
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  7. Review
  8. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Peter D FriedmannOffice of Research, University of Massachusetts Chan Medical School-Baystate, Baystate Health, Springfield.ORCID 0000-0003-3585-3604
Donna WilsonOffice of Research, University of Massachusetts Chan Medical School-Baystate, Baystate Health, Springfield.
Thomas J StopkaDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston.
Dana BernsonMassachusetts Department of Public Health, Office of Population Health, Boston.
Ekaterina PivovarovaDepartment of Family Medicine and Community Health, University of Massachusetts Chan Medical School, Worcester.
Warren FergusonDepartment of Family Medicine and Community Health, University of Massachusetts Chan Medical School, Worcester.
Randall A HoskinsonOffice of Research, University of Massachusetts Chan Medical School-Baystate, Baystate Health, Springfield.
Rebecca E RottapelDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston.
Benjamin Bovell-AmmonDepartment of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School-Baystate, Baystate Health, Springfield.
Ayorkor GabaDepartment of Counseling and Clinical Psychology, Teachers College, Columbia University, New York.
Jake R MorganDepartment of Health Law, Policy, and Management, Boston University School of Public Health, Boston.ORCID 0000-0002-1559-3983
Thomas SenstMiddlesex County Sheriff's Department, Woburn, MA.
Edmond HayesFranklin County Sheriff's Department, Greenfield, MA.
Elizabeth A EvansDepartment of Health Promotion and Policy, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst.ORCID 0000-0002-3478-9957
MassJCOIN Research Hub

Funding

Massachusetts Justice Cooperative Opioid Innovation Network (JCOIN) Research CenterUG1DA050067 · NIDA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI EVANS, ELIZABETH A. · 2019 to 2023
$10.5M
Increasing Referrals to Medications for Opioid Use Disorders from Drug Treatment Courts using Organizational Linkage InterventionK23DA049953 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PIVOVAROVA, EKATERINA · 2020 to 2022
$612k
NIDA NIH HHS K23 DA049953NIDA NIH HHS UG1 DA050067NIH HHS 1UG1DA050067NIH HHS 5K23DA049953
6 · The paper itself

Abstract

backgroundIn 2019, seven county correctional facilities (jails) in Massachusetts initiated pilot programs to provide all Food and Drug Administration-approved medications for opioid use disorder (MOUD).

methodsThis observational study used linked state data to examine postrelease MOUD receipt, overdose, death, and reincarceration among persons with probable opioid use disorder (OUD) in carceral settings who did or did not receive MOUD from these programs from September 1, 2019, through December 31, 2020. Log-binomial and proportional-hazards models were adjusted for propensity-score weights and baseline covariates that remained imbalanced after propensity-score weighting.

resultsThe study cohort included 6400 persons with probable OUD: 2711 (42.4%) received MOUD in jail and 3689 (57.6%) did not. Among persons treated with MOUD in jail, 67.9% received buprenorphine, 25.7% received methadone, and 6.5% received naltrexone. Treated persons were more likely than those not treated to be White (75.4% vs. 58.1%), to be sentenced (31.6% vs. 13.2%), to be receiving MOUD at jail entry (73.7% vs. 17.1%), and to receive MOUD during the first 30 days after community release (60.2% vs. 17.6%; adjusted relative risk, 1.44; 95% confidence interval [CI], 1.38 to 1.50). Only 50.4% of MOUD recipients engaged in MOUD treatment for 75% of the first 90 days after release, and 57.5% were receiving MOUD at 180 days. Receipt of MOUD in jail, as compared with no such receipt, was associated with lower postrelease risks of fatal overdose (adjusted hazard ratio, 0.48; 95% CI, 0.36 to 0.64), nonfatal overdose (adjusted hazard ratio, 0.76; 95% CI, 0.68 to 0.85), death from any cause (adjusted hazard ratio, 0.44; 95% CI, 0.35 to 0.56), and reincarceration (adjusted hazard ratio, 0.88; 95% CI, 0.81 to 0.94). The incidence of hospitalizations did not differ substantially between the two groups.

conclusionsReceipt of MOUD in jail was associated with an increased likelihood of postrelease MOUD initiation and decreased risks of overdose, death from any cause, and reincarceration. (Funded by the National Institutes of Health and others.).

Indexed as

Analgesics, OpioidJailsNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPrisonersAdultBuprenorphineFemaleHospitalizationHumansIncarcerationMaleMassachusettsMethadoneNaltrexoneAnalgesics, OpioidBuprenorphineMethadoneNaltrexoneNarcotic Antagonists

Identifiers

PMID40929634
PMCPMC12646036

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.