Evidence map›Paper›PMID 40929128›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Utility of GERAADA Score for Predicting Long-term Survival Following Surgical Repair of Aortic Dissection.

Francesco Pollari, Paolo Nardi, Elisa Mikus, Francesco Ferraro, Marco Gemelli, Ilaria Franzese, Ilaria Chirichilli, Claudia Romagnoni, Giuseppe Santarpino, Salvatore Nicolardi and 14 more

Abstract readMulticenter Study
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Francesco PollariDepartment of Cardiac Surgery, Klinikum Nürnberg-Paracelsus Medical University, Nuremberg, 90471, Germany.ORCID 0000-0003-1729-532X
Paolo NardiCardiac Surgery, Tor Vergata Policlinic University, Tor Vergata University of Rome, Rome, 00133, Italy.
Elisa MikusDepartment of Cardiac Surgery, Maria Cecilia Hospital, GVM Care & Research, Cotignola, 48033, Italy.
Francesco FerraroCardiovascular Sciences Department, Agostino Gemelli Foundation Polyclinic IRCCS, Catholic University of the Sacred Heart, Rome, 00168, Italy.
Marco GemelliCardiac Surgery, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padua, 35128, Italy.
Ilaria FranzeseCardiac Surgery, Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, 34128, Italy.ORCID 0000-0003-2676-0457
Ilaria ChirichilliDepartment of Cardiac Surgery and Heart Transplantation, San Camillo Forlanini Hospital, Rome, 00152, Italy.ORCID 0000-0003-1354-9599
Claudia RomagnoniCardiac Surgery, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, 20122, Italy.
Giuseppe SantarpinoDepartment of Cardiac Surgery, Città di Lecce Hospital, GVM Care & Research, Lecce, 73100, Italy.ORCID 0000-0002-4913-9834
Salvatore NicolardiCardiac Surgery, "Vito Fazzi" Hospital, Lecce, 73100, Italy.
Roberto ScrofaniCardiac Surgery, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, 20122, Italy.
Federico RanocchiDepartment of Cardiac Surgery and Heart Transplantation, San Camillo Forlanini Hospital, Rome, 00152, Italy.
Enzo MazzaroCardiac Surgery, Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, 34128, Italy.
Gino GerosaCardiac Surgery, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padua, 35128, Italy.ORCID 0000-0002-6261-699X
Massimo MassettiCardiovascular Sciences Department, Agostino Gemelli Foundation Polyclinic IRCCS, Catholic University of the Sacred Heart, Rome, 00168, Italy.
Carlo SaviniDepartment of Cardiac Surgery, Maria Cecilia Hospital, GVM Care & Research, Cotignola, 48033, Italy.
Giovanni RuvoloCardiac Surgery, Tor Vergata Policlinic University, Tor Vergata University of Rome, Rome, 00133, Italy.
Luca Di MarcoCardiac Surgery, IRCCS, Azienda Ospedaliero Universitaria di Bologna, Bologna, 40138, Italy.
Oriana D'EcclesiisItalian National Agency for Regional Healthcare Services (AGENAS), Rome, 00187, Italy.
Emma GuagneliItalian National Agency for Regional Healthcare Services (AGENAS), Rome, 00187, Italy.
Giorgia DurantiItalian National Agency for Regional Healthcare Services (AGENAS), Rome, 00187, Italy.ORCID 0000-0001-9436-630X
Alessandro ParolariUniversity Unit of Cardiac Surgery, IRCCS Policlinico S. Donato, S. Donato Milanese, 20097, Italy.
Fabio BariliDepartment of Biomedical and Clinical Sciences, Universitá degli Studi di Milano, Milan, 20133, Italy.
GIROC (Italian Research Group on Outcome in Cardiac Surgery)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to assess the long-term survival following surgical repair because of acute type A aortic dissection (ATAAD) and the correlation with the preoperative GERAADA (German Registry for Acute Type A Aortic Dissection)-score value.

methodsWe enrolled patients who underwent emergent aortic surgery because of ATAAD from 2010 to 2022 from 9 hospitals. Follow-up information was obtained by matching the clinical patient data with a national administrative database. Discrimination and calibration of GERAADA were tested at 1, 2, 5, and 10 years. The relationship between long-term outcome and score was also tested through time-to-event methods.

resultsA total of 1110 patients were analysed: Median age was 67 years [IQR 57-75], and 30.8% of subjects were female. Median GERAADA score was 14.3% [10.2-22]. Mean length of follow-up was 4.19 years. The Kaplan-Meier estimates of survival at 5 and 10 years were, respectively, 62.5% ± 1.5%, and 48.5% ± 2.1%. Discrimination was poor but remained stable over the time (area under the curve [AUC] at 1-year follow-up: 0.66; 95% CI 0.63-0.70. AUC at 10-year follow-up: 0.64; 95% CI 0.61-0.68). Calibration plots showed underprediction until 50%-predicted probability and progressive overprediction afterward. There is a steep mortality in the first couple of months after surgery while afterward the mortality rate is constantly lower. GERAADA score was found to be a predictor of long-term mortality with a nonlinear association.

conclusionsGERAADA score showed a poor performance in predicting long-term survival.

Indexed as

Aortic AneurysmAortic DissectionDecision Support TechniquesAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment Outcomeaortic dissectionlong-term outcomesrisk scores

Identifiers

PMID40929128
PMCPMC12448939

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