ArticlePLOS global public health2025
A deadly equation: The global toll of US TB funding cuts.
Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The trial behind it
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Who cites it
23 citing papers in PubMed.
- Engaging tuberculosis-affected people in investment decisions: applying a people-centered design approach in Viet Nam.BMC public health · 2026Article
- Illicit substance use and its impact on tuberculosis care engagement: A systematic review and Meta-analysis of prevalence.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Review
- A model for the epidemiological impact of tuberculosis policy options.Bulletin of the World Health Organization · 2026Article
- Priority-setting in TB programme planning: guiding an equitable and effective response.IJTLD open · 2026Article
- Implications of year 1 Trump Administration policies for Americans' lung health.American journal of respiratory and critical care medicine · 2026Article
- Targeting Tryptophan Metabolism for Tuberculosis Biomarkers and Host-Directed Therapy.The Journal of infectious diseases · 2026Review
- Impact of US government funding freezes on the HIV response: findings from a rapid survey in 32 countries.Health affairs scholar · 2026Article
- Temporal trends and associations between domestic public health spending, donor funding and tuberculosis outcomes in Africa: a serial cross-sectional study (1990-2022).BMJ public health · 2026Article
- Mobilizing the banking sector for universal health coverage: a new frontier for public-private partnerships.Frontiers in health services · 2026Article
- Cost and impact of decentralized tuberculosis testing: a modeling analysis of price thresholds for molecular instruments in high-burden settings.EClinicalMedicine · 2026Article
- From pilot to policy: why AI health interventions fail to scale in developing countries.Frontiers in digital health · 2026Article
- Water against stone: PLOS Global Public Health's persistence in the pursuit of equity in public health.PLOS global public health · 2026Article
- Converting donor dependence to domestic ownership: The realignment of tuberculosis financing for sustainability.PLOS global public health · 2026Article
- The domino effect: projecting the effects of US funding cuts to health aid in the global south.The Lancet regional health. Southeast Asia · 2025Article
- Financing the future of TB control: from dependence to resilience.Public health action · 2025Article
- US divestment in global health: disruption, uncertainty and response.BMJ global health · 2025Review
- From dependence to self-reliance: The future of the global tuberculosis response.PLoS medicine · 2025Article
- Effects of reductions in US foreign assistance on HIV, tuberculosis, family planning, and maternal and child health: a modelling study.The Lancet. Global health · 2025Article
- Tuberculosis at the crossroads: urgent actions for migrant and refugee health in a turbulent era.BMJ global health · 2025Review
- Optimizing TB policies using the global TB portfolio model: an economic analysis.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent withdrawal of U.S. financial support threatens essential TB service delivery, including diagnostics, treatment, TB-HIV co-infection interventions and research initiatives critical to eradicating TB. This study analyses the dependency of and potential impact of funding cuts to 26 high-burden TB countries (HBCs). We modelled three recovery scenarios: (1) minimal impact (services recover within three months), (2) moderate impact (recovery within one year), and (3) worst-case scenario (long-term service reduction). Extrapolations were made for all 26 HBCs based on representative countries from each dependency category. Across all 26 HBCs, additional TB cases between 2025 and 2030 are estimated at 0.63 million (CI 0.45-0.81) (minimal impact), 1.66 million (CI 1.2-2.1) (moderate impact), and 10.67 million (CI 7.85-13.19) (worst-case). Corresponding TB deaths are projected to increase by 99,900 (CI 65,200-130,000), 268,600 (CI 185,800-337,900), and 2,243,700 (CI 1,570,800-2,807,300), respectively. The loss of U.S. funding endangers global TB control efforts, jeopardizing progress towards End TB and SDG targets, and potentially puts millions of lives at risk. While some nations may adapt, short-term disruptions will severely impact vulnerable populations. Urgent alternative funding is needed to sustain critical TB prevention and treatment efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.