Evidence map›Paper›PMID 40928870›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Binding of

Fan Shen, Linjie Li, Dongchun Yang, Zhexiao Tang, Lu Zhang, Kefang Liu, Wenzhe Hou, Zhuozhuang Lu, Jing-Yuan Fang, Jianxun Qi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The role of adhesins ofGut microbes · 2026
    Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fan Shen *Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Linjie Li *Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Dongchun Yang *State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Zhexiao TangKey Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Lu ZhangDivision of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, National Health Commission of the People's Republic of China Key Laboratory of Digestive Diseases, State Key Laboratory of Systems Medicine for Cancer, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Kefang LiuKey Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Wenzhe HouNational Health Commission of the People's Republic of China Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.
Zhuozhuang LuNational Health Commission of the People's Republic of China Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.
Jing-Yuan FangDivision of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, National Health Commission of the People's Republic of China Key Laboratory of Digestive Diseases, State Key Laboratory of Systems Medicine for Cancer, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Jianxun QiKey Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-9358-4732
Xin ZhaoKey Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
George F GaoKey Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-3869-615X

Funding

Chinese Academy of Sciences Project for Young Scientists in Basic Research YSBR-083MOST | National Key Research and Development Program of China (NKPs) 2020YFA0509202MOST | National Key Research and Development Program of China (NKPs) 2025YFC2311800MOST | National Natural Science Foundation of China (NSFC) 82222040Special Program of China National Tobacco Corporation 2024200CB0160Special Program of China National Tobacco Corporation 2024600CB0070
6 · The paper itself

Abstract

In eukaryotic systems, three major types of cell junctions have been well characterized. While bacterial adhesion mechanisms also exhibit remarkable diversity, the molecular processes that regulate the dynamic modulation of binding strength between elongated bacterial cells and host cells remain poorly understood.

Indexed as

Adhesins, BacterialAntigens, CDBacterial AdhesionCell Adhesion MoleculesFusobacterium nucleatumCarcinoembryonic AntigenCEACAM1 ProteinGPI-Linked ProteinsHumansProtein BindingAdhesins, BacterialAntigens, CDCarcinoembryonic AntigenCD66 antigensCEACAM1 ProteinCEACAM5 protein, humanCell Adhesion MoleculesGPI-Linked ProteinsCbpF adhesinCEACAM1CEACAM5Fusobacterium nucleatumVelcro-like binding

Identifiers

PMID40928870
PMCPMC12452904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.