Evidence map›Paper›PMID 40928694›Full record

ArticleInternational urogynecology journal2025

Cross-Sectional Associations of Depressive Symptoms, Anxiety Symptoms, and Emotional Support Seeking with Lower Urinary Tract Symptoms and Bladder Health.

Sonya S Brady, Deepa R Camenga, Tamera Coyne-Beasley, Chloe Falke, Colleen M Fitzgerald, Bernard L Harlow, Kimberly Kenton, Heather Klusaritz, Cora E Lewis, Dulce P Rodriguez-Ponciano and 7 more

Abstract read
In one paragraph

Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Sonya S BradyDepartment of Family Medicine and Community Health, Program in Health Disparities Research, University of Minnesota Medical School, 717 Delaware Street SE, Suite 166, Minneapolis, MN, 55414, USA. ssbrady@umn.edu.ORCID 0000-0001-8660-9308
Deepa R CamengaDepartment of Emergency Medicine & Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Tamera Coyne-BeasleyHeersink School of Medicine, Department of Pediatrics, Division of Adolescent Medicine, Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Chloe FalkeDivision of Biostatistics and Health Data Science, University of Minnesota School of Public Health, Minneapolis, MN, USA.
Colleen M FitzgeraldDepartment of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Chicago, IL, USA.
Bernard L HarlowDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Kimberly KentonDepartment of Obstetrics & Gynecology, Section of Urogynecology & Reconstructive Pelvic Surgery, University of Chicago, Chicago, IL, USA.
Heather KlusaritzDivision of Community Health, Department of Family Medicine & Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Cora E LewisSchool of Public Health, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Dulce P Rodriguez-PoncianoDepartment of Obstetrics, Gynecology and Reproductive Sciences, Division of Urogynecology and Reconstructive Surgery, University of California San Diego, La Jolla, CA, USA.
Kyle D RudserDivision of Biostatistics and Health Data Science, University of Minnesota School of Public Health, Minneapolis, MN, USA.
Abigail R SmithDepartment of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ariana L SmithDepartment of Surgery, Division of Urology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Siobhan SutcliffeDepartment of Obstetrics and Gynecology, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Eliza Wilson-PowersDepartment of Health Behavior and Biological Sciences, University of Michigan School of Nursing, Ann Arbor, MI, USA.
Shayna D CunninghamDepartment of Public Health Sciences, University of Connecticut School of Medicine, Farmington, CT, USA.
Prevention of Lower Urinary Tract Symptoms Research Consortium

Funding

Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Scientific and Data Coordinating CenterU24DK106786 · NIDDK · UNIVERSITY OF MINNESOTA · PI MCGWIN, GERALD, RUDSER, KYLE · 2020 to 2024
$7.1M
University of Pennsylvania+ PLUS Clinical Center (PENN+PLUS CC)U01DK106892 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI NEWMAN, DIANE K., SMITH, ARIANA L · 2015 to 2024
$5.4M
PLUS Loyola Clinical CenterU01DK106898 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, FITZGERALD, COLLEEN MARIE · 2015 to 2024
$4.7M
Prevention of LUTS: Bladder Health Clinical Center, UC San Diego SiteU01DK106827 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACOURSIERE, DAPHNE YVETTE, LUKACZ, EMILY S. · 2015 to 2024
$4.5M
Pathways to LUTS Prevention: A Model for Public Education, Behavioral Skills, and Early DetectionU01DK106858 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCGWIN, GERALD · 2015 to 2024
$4.5M
LUTS PREVENTION IN ADOLESCENT GIRLS AND WOMEN ACROSS THE LIFESPANU01DK106853 · NIDDK · WASHINGTON UNIVERSITY · PI SUTCLIFFE, SIOBHAN · 2015 to 2024
$4.0M
The Truly Healthy Bladder: Understanding Normal As A Pathway To Prevention Of Lower Urinary Tract Symptoms In WomenU01DK106893 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOW, LISA KANE · 2015 to 2024
$3.8M
Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Yale Clinical Research CenterU01DK106908 · NIDDK · YALE UNIVERSITY · PI RICKEY, LESLIE M. · 2015 to 2024
$3.5M
NORTHWESTERN UNIVERSITY PLUS CLINICAL SITEU01DK126045 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GRIFFITH, JAMES WILLIAM, SIMON, MELISSA A. · 2020 to 2024
$1.4M
NIDDK NIH HHS U01 DK106827NIDDK NIH HHS U01DK106827NIDDK NIH HHS U01 DK106853NIDDK NIH HHS U01DK106853NIDDK NIH HHS U01 DK106858NIDDK NIH HHS U01DK106858NIDDK NIH HHS U01 DK106892NIDDK NIH HHS U01DK106892NIDDK NIH HHS U01 DK106893NIDDK NIH HHS U01DK106893NIDDK NIH HHS U01 DK106898NIDDK NIH HHS U01DK106898NIDDK NIH HHS U01 DK106908NIDDK NIH HHS U01DK106908NIDDK NIH HHS U01 DK126045NIDDK NIH HHS U01DK126045NIDDK NIH HHS U24 DK106786NIDDK NIH HHS U24DK106786
6 · The paper itself

Abstract

introduction and hypothesisDepressive and anxiety symptoms are known risk factors for lower urinary tract symptoms (LUTS). To inform prevention and treatment strategies, this research examined whether greater emotional support seeking weakened associations of affective symptoms with LUTS and poorer bladder health.

methodsData were collected from women in the USA who participated in the RISE FOR HEALTH study of bladder health. In this cross-sectional analysis (analytic sample n = 1444), self-reported LUTS, perceived bladder health, and perceived impact of bladder health on five domains of living (social and occupational activities, travel, physical activities, intimacy, and emotions) were separately regressed on depressive symptoms, anxiety symptoms, and emotional support seeking. Interaction tests examined whether emotional support seeking modified associations of affective symptoms with LUTS and bladder health.

resultsReport of worse depressive symptoms, worse anxiety symptoms, and lower levels of engagement in emotional support seeking were associated with more frequent LUTS, poorer perceived bladder health, and lower perceived positive impact of bladder health on each domain of living. Emotional support seeking was not associated with LUTS and bladder health outcomes when adjusting for affective symptoms, and did not modify associations of affective symptoms with LUTS and bladder health outcomes.

conclusionsIntervention research to prevent LUTS and promote bladder health can test strategies that include screening and providing timely treatment of affective symptoms. Health care providers treating women for LUTS can screen for affective symptoms and make referrals to ensure that both the physical health and the mental health needs of patients are being met.

Indexed as

AnxietyDepressionLower Urinary Tract SymptomsSocial SupportAdultAgedCross-Sectional StudiesFemaleHumansMiddle AgedUnited StatesUrinary BladderAnxietyBladder healthCopingDepressionLower urinary tract symptomsSocial support

Identifiers

PMID40928694
PMCPMC12680009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.