SynthesisSleep & breathing = Schlaf & Atmung2025
Eustachian tube dysfunction in obstructive sleep apnea patients: implications for a multimodal treatment approach. A systematic review.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIt is well known that Obstructive Sleep Apnea (OSA) is a complex disease characterized by an Upper Airway (UA) collapse during sleep, with potential consequences on ENT districts. Recent evidence suggests a possible association with Eustachian Tube Dysfunction (ETD). However, the potential effects of both surgical and non-surgical therapeutic strategies on ET function remain poorly explored in the current literature. This review aims to analyze the correlation between OSA and ETD, and to evaluate how invasive and non-invasive treatment OSA strategies influence ET function.
methodsAn electronic search was performed on PubMed/MEDLINE, Google Scholar, and Ovid databases using keywords as "eustachian tube," "eustachian tube dysfunction," "OSA," "obstructive sleep apnea," "pharyngeal surgery," and "CPAP." Additional cross-referencing was performed to identify relevant studies. The last search was completed in July 2024.
resultsOut of the 334 identified articles, 15 met the inclusion criteria, encompassing 125,178 patients. Studies were categorized into three groups: correlation between OSA and ETD (n = 6), effects of CPAP on ETD (n = 6), and outcomes of pharyngeal surgery on ET function (n = 3). CPAP use was associated with improved ETD symptoms and middle ear pressure. Postoperative ETD worsening was noted after pharyngeal surgery due to tissue edema and inflammation.
conclusionETD appears to be a prevalent comorbidity in OSA patients. While CPAP shows a beneficial effect on ET function, surgical outcomes are less clear. Larger studies are needed to clarify these associations and guide therapeutic decisions in OSA management.
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Registered trials
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