Evidence map›Paper›PMID 40928674›Full record

ReviewDiabetologia2025

Global challenges in diabetes research and care: which way forward? An appraisal from the EASD Global Council.

Francesco Giorgino, Fawaz Alzaid, Anca Pantea Stoian, Juliana C N Chan, Linong Ji, William Lumu, Helard Manrique, Didac Mauricio, Banshi Saboo, Peter A Senior and 5 more

Abstract readReview
In one paragraph

Review in Diabetologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Francesco GiorginoDepartment of Precision and Regenerative Medicine and Ionian Area, Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy. francesco.giorgino@uniba.it.ORCID http://orcid.org/0000-0001-7372-2678
Fawaz AlzaidDasman Diabetes Institute, Kuwait City, Kuwait.ORCID http://orcid.org/0000-0003-3056-3640
Anca Pantea StoianDiabetes, Nutrition and Metabolic Diseases Department, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
Juliana C N ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, HKSAR, China.ORCID http://orcid.org/0000-0003-1325-1194
Linong JiPeking University Diabetes Center, Peking University People's Hospital, Beijing, China.ORCID http://orcid.org/0000-0002-3262-2168
William LumuDepartment of Endocrinology and Non-Communicable Diseases, Mengo Hospital, Kampala, Uganda.ORCID http://orcid.org/0000-0002-4530-8012
Helard ManriqueDepartment of Diabetes, Endocrinology and Nutrition, Delgado Clinic and Diabetes, Obesity Nutrition Research, Lima, Perú.ORCID http://orcid.org/0000-0002-5064-6147
Didac MauricioDepartment of Endocrinology & Nutrition, CIBERDEM - IR Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-2868-0250
Banshi SabooDiacare - Diabetes Care and Hormone Clinic, Ahmedabad, India.ORCID http://orcid.org/0000-0001-7293-8864
Peter A SeniorAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.ORCID http://orcid.org/0000-0003-1033-8673
Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID http://orcid.org/0000-0002-5334-7687
Sophia ZoungasSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0003-2672-0949
Manuela MeirelesEuropean Association for the Study of Diabetes Office, Düsseldorf, Germany.ORCID http://orcid.org/0000-0003-3703-0011
Chantal MathieuEndocrinology UZ Gasthuisberg, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-4055-5233
Leszek CzupryniakDepartment of Diabetology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.ORCID http://orcid.org/0000-0003-2396-8885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article, developed by the EASD Global Council, addresses the growing global challenges in diabetes research and care, highlighting the rising prevalence of diabetes, the increasing complexity of its management and the need for a coordinated international response. With regard to research, disparities in funding and infrastructure between high-income countries and low- and middle-income countries (LMICs) are discussed. The under-representation of LMIC populations in clinical trials, challenges in conducting large-scale research projects, and the ethical and legal complexities of artificial intelligence integration are also considered as specific issues. The development of global research networks and strategies for improved training, standardisation of data and enhanced accessibility to big data analytics to drive innovation and personalised medicine are recommended. With regard to diabetes care, inequalities in access to essential medications, particularly insulin and novel therapies, and disparities in healthcare infrastructure are discussed. Proposed initiatives include international support programmes, improved healthcare provider training and the inclusion of newer diabetes medications in essential drug lists. The importance of global screening programmes, a universal diabetes education curriculum and standardised healthcare checklists is also emphasised. Regarding healthcare organisation, the development of national diabetes registers, benchmarking performance across regions and strengthening international collaborations are highly advised. The role of diabetes specialists as care coordinators and the need for structured assessments to improve early intervention and long-term outcomes are also discussed. Ultimately, the EASD Global Council urges action for a unified, global approach to diabetes research and care to bridge the gap between scientific innovation and clinical practice, ensuring equitable healthcare worldwide.

Indexed as

Biomedical ResearchDiabetes MellitusGlobal HealthHumansArtificial intelligenceBig dataClinical trialsDiabetesDiabetes registersDigital healthEducation and trainingEquity, diversity and inclusionHealth systemsLow- and middle-income countriesPersonalised medicineReview

Identifiers

PMID40928674
PMCPMC12534272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.