Evidence map›Paper›PMID 40928665›Full record

Trial reportWorld journal of urology2025

Impact of pad wetness on health-related quality of life after radical cystectomy and orthotopic neobladder.

Riccardo Mastroianni, Andrea Iannuzzi, Alberto Ragusa, Gabriele Tuderti, Umberto Anceschi, Alfredo Maria Bove, Aldo Brassetti, Simone D'Annunzio, Mariaconsiglia Ferriero, Leonardo Misuraca and 3 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Riccardo MastroianniUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Andrea IannuzziResearch Unit of Urology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy. andrea.iannuzzi@unicampus.it.
Alberto RagusaResearch Unit of Urology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Gabriele TudertiUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Umberto AnceschiUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Alfredo Maria BoveUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Aldo BrassettiUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Simone D'AnnunzioUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Mariaconsiglia FerrieroUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Leonardo MisuracaUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Salvatore GuaglianoneUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Rocco PapaliaDepartment of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Giuseppe SimoneUro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the impact of day- and night-time pad wetness on 2yrs-QoL after Radical Cystectomy (RC) with Orthotopic Neobladder (ON) from a Randomized Controlled Trial (RCT) aimed at comparing open RC (ORC) and Robot-Assisted RC (RARC) with intracorporeal (i) ON.

methodsBetween January 2018 and September 2020, 116 patients were enrolled. Data from self-assessed questionnaires (EORTC-QLQ-C30 and QLQ-BLM30) were collected. Unmodified HRQoL was defined as a 2yrs Global Health status/QoL increase ≥ 0 (ΔQL ≥ 0) from baseline. Quantitative analysis of continence status was evaluated through 3-day voiding diaries. We previously defined day-time continence as "complete dryness" (0gr pad wetness) and night-time continence as pad wetness ≤ 50gr.

resultsOut of 116 patients enrolled, 88 received ON, and 71 with a minimum 2yrs follow-up were included. Quantitative analysis of day- and night-time urinary continence are reported. Particularly, 44 patients (62%) were completely dry during the day, while 40 patients (57%) experienced night-time pad wetness ≤ 50gr. However, a day pad wetness > 0gr significantly impact on 2yrs unmodified Global Health Status (p = 0.029), while only a night-time pad wetness ≥ 500gr significantly impacts on 2yrs unmodified Global Health Status (p = 0.005).

conclusionThis study strengthens the need for a strict definition of day-time urinary continence after RC and ON, confirming complete dryness as a main driver of patients' HRQoL. Conversely, nigh-time continence status seems to play a negligible role on subjectively assessed HRQoL.

Indexed as

CystectomyIncontinence PadsPostoperative ComplicationsQuality of LifeUrinary Bladder NeoplasmsUrinary IncontinenceUrinary Reservoirs, ContinentAgedFemaleHumansMaleMiddle AgedHRQoLNeobladderPad wetnessRadical cystectomyRARC

Identifiers

PMID40928665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.