Evidence map›Paper›PMID 40928536›Full record

Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

The predictive value of the orientation and offset of angle α and angle κ for visual outcomes after trifocal intraocular lens implantation in an Asian cohort.

Xia Zhang, Shuang Song, Wenda Sui, Lu Sun, Zaowen Wang, Lulu Chen, Ailing Bian, Yong Zhong, Shunhua Zhang

Abstract readObservational Study
In one paragraph

Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xia ZhangDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.ORCID http://orcid.org/0009-0001-5748-4371
Shuang SongDepartment of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1903-090X
Wenda SuiDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Lu SunDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Zaowen WangDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Lulu ChenDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.ORCID http://orcid.org/0009-0002-3673-667X
Ailing BianDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Yong ZhongDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Shunhua ZhangDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing. pumchzhang@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the predictive value of the preoperative orientation and offset of angle alpha(chord alpha) and angle kappa(chord mu) for visual outcomes in patients who underwent trifocal intraocular lens (IOL) implantation.

methodsPatient records of eyes that underwent AT LISA tri 839MP implantation were retrospectively collected and grouped according to the preoperative offset and orientations of chord alpha and chord mu. The two-dimensional location of each angle was described by the interaction of the orientation and offset. Multiple regression models and likelihood ratio tests were established to determine their predictive value for postoperative visual outcomes, National Eye Institute Visual Function Questionnaire (NEI-VFQ) and Quality of Vision Questionnaire (QoV) scores.

resultsOne hundred and two patients (184 eyes) were included. The orientation of chord alpha had a significant overall prediction to postoperative visual outcomes (p = 0.014). A superior chord alpha was an independent predictor of better postoperative uncorrected distance visual acuity (UDVA, p < 0.001) and a larger modulation transfer function (MTF) curve average height (p = 0.041). However, the offsets of chords alpha and chord mu and the orientation of chord mu did not significantly predict UDVA, uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), MTF, total ocular aberration (TOA), or high-order aberration (HOA).Better patient reported general vision was correlated with a nasal chord alpha (p = 0.012), whereas better near vision was correlated with a smaller kappa offset (p = 0.022) and nasal chord alpha (p = 0.019). The absence of postoperative halos was independently associated with the location of nasal chord alpha(p = 0.039), while starbursts were independently correlated with a larger chord mu offset (p = 0.007).

conclusionA superior chord alpha was an independent predictor of better postoperative visual outcomes after trifocal IOL implantation. The predictive value of either the orientation or offset of chord mu for the VA, TOA and HOA was insignificant.

trial registrationNot applicable. KEY MESSAGES: What is known The chord alpha (angle alpha) was found to be predominantly located in the temporal quadrant of the cornea, followed by the superior, nasal, and inferior quadrants. The chord mu (angle kappa) was more evenly distributed in the four quadrants, with 46.2% (85/184) in the temporal quadrant, followed by the inferior, superior, and nasal quadrants. What this paper adds A superior chord alpha orientation was an independent predictor of better postoperative uncorrected distance visual acuity (UDVA) and modulation transfer function average height (MTF AH). However, the interaction of orientation and offset had no predictive value. The orientation and offset of chord mu had no significant predictive value for UDVA, uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), MTF AH, total (TOA), or high-order aberration (HOA). The nasal chord alpha was independently correlated with better patient reported general vision, near vision and absence of halo. A smaller kappa offset was independently correlated with better performance in patient reported near vision and fewer starbursts.

Indexed as

Cataract ExtractionCorneaLens Implantation, IntraocularMultifocal Intraocular LensesVisual AcuityAdultAgedAged, 80 and overCorneal TopographyFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesAberrationAngle alphaAngle kappaChord alphaChord muMultifocal intraocular lensPatient-reported visual outcomeVisual acuity

Identifiers

PMID40928536
PMCPMC12675633

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.