Evidence map›Paper›PMID 40928424›Full record

ArticleNeuropathology and applied neurobiology2025

A Novel Neuropathological Subtype of Amyotrophic Lateral Sclerosis Characterised by Prominent Astroglial TDP-43 Pathology.

Tomoyasu Matsubara, Yuishin Izumi, Yuki Hatanaka, Mika Takahara, Amuro Kondo, Kiyoshi Matsukura, Akira Arakawa, Toshihiro Haga, Ryosuke Miyamoto, Hiroya Naruse and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropathology and applied neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Flail Limb Syndrome.Muscle & nerve · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tomoyasu MatsubaraDepartment of Neuropathology (The Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID https://orcid.org/0000-0002-7559-8284
Yuishin IzumiDepartment of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.ORCID https://orcid.org/0000-0002-3048-9041
Yuki HatanakaDepartment of Neurology, Teikyo University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3365-8506
Mika TakaharaDepartment of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Amuro KondoDepartment of Neurology, Teikyo University School of Medicine, Tokyo, Japan.
Kiyoshi MatsukuraDepartment of Neurology, Teikyo University School of Medicine, Tokyo, Japan.
Akira ArakawaDepartment of Neuropathology (The Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9336-1168
Toshihiro HagaDepartment of Diagnostic Pathology, Teikyo University Hospital, Tokyo, Japan.
Ryosuke MiyamotoDepartment of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.ORCID https://orcid.org/0000-0001-6434-9541
Hiroya NaruseDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki MorinoDepartment of Medical Genetics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tatsushi TodaDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Shigeo MurayamaDepartment of Neuropathology (The Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9709-5242
Yuko SaitoDepartment of Neuropathology (The Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.

Funding

AMED JP21wm0425019AMED JP24tm0524002Integrated Research Initiative for Living Well with Dementia (IRIDE) of the Tokyo Metropolitan Institute for Geriatrics and GerontologyJSPS KAKENHI JP22H04923JSPS KAKENHI JP22K15740JSPS KAKENHI JP24K18698Kato Memorial Bioscience FoundationMedical Research Grants of Takeda Science FoundationMHLW Research on rare and intractable diseases Program JPMH23FC1008Yukihiko Miyata Memorial Trust for ALS Research
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyotrophic lateral sclerosisastrocyteautopsyflail arm syndromemotor neuron diseaseTDP‐43

Identifiers

PMID40928424
PMCPMC12422077

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.