Evidence map›Paper›PMID 40928300›Full record

ArticleMicrobiology spectrum2025

Genomic insights into a diarrheal outbreak in Bangladesh reveal novel ETEC lineages and expansion of CS23 colonization factor.

Sadia Isfat Ara Rahman, Mohammad Jubair, Marjahan Akhtar, Afroza Akter, Imam Tauheed, Yasmin Ara Begum, Piyash Bhattacharjee, Mokibul Hassan Afrad, Farhana Khanam, Md Taufiqul Islam and 9 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sadia Isfat Ara RahmanInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-7983-087X
Mohammad JubairInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Marjahan AkhtarInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Afroza AkterInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Imam TauheedInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Yasmin Ara BegumInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Piyash BhattacharjeeInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mokibul Hassan AfradInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Farhana KhanamInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Md Taufiqul IslamInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Ashraful Islam KhanInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mustafizur RahmanInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-6876-0191
Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0009-0005-0169-394X
James M FleckensteinThe Molecular Microbiology and Microbial Pathogenesis Program, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, Missouri, USA.
Taufiqur Rahman BhuiyanInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0003-3755-4763
Nicholas Robert Thomson *Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Firdausi Qadri *International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-8928-9888
Astrid von Mentzer *Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-2167-1394
Fahima Chowdhury *International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-7082-0720

Funding

Novel Antigen Identification for an Enterotoxigenic E. coli VaccineR01AI089894 · NIAID · WASHINGTON UNIVERSITY · PI Zachary T. Berndsen, James Michael Fleckenstein · 2010 to 2026
$7.4M
Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
FIC NIH HHS D43 TW005572NIAID NIH HHS R01 AI089894Wellcome Trust
6 · The paper itself

Abstract

Enterotoxigenic

Indexed as

DiarrheaDisease OutbreaksEnterotoxigenic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFimbriae ProteinsBangladeshDrug Resistance, Multiple, BacterialGenome, BacterialGenomicsHumansPhylogenyVirulenceVirulence FactorsWhole Genome Sequencingcolonization factor antigensEscherichia coli ProteinsFimbriae ProteinsVirulence FactorsBangladeshcolonization factorsdiarrheaenterotoxigenic E. colitoxin profilewhole genome sequencing

Identifiers

PMID40928300
PMCPMC12502627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.