Evidence map›Paper›PMID 40928299›Full record

ArticlemBio2025

Chemical stimuli override a temperature-dependent morphological program by reprogramming the transcriptome of a fungal pathogen.

Dror Assa, Mark Voorhies, Anita Sil

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Dror AssaDepartment of Microbiology and Immunology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0001-7301-1358
Mark VoorhiesDepartment of Microbiology and Immunology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0001-8815-7384
Anita SilDepartment of Microbiology and Immunology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-3987-7534

Funding

Gene circuits that control morphology in HistoplasmaR37AI066224 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Anita Sil · 2020 to 2026
$3.3M
Chan-Zuckerberg Biohub San Francisco Investigator AwardNational Institute of Allergy and Infectious Diseases 2R37AI066224NIAID NIH HHS R37 AI066224
6 · The paper itself

Abstract

The human fungal pathogen

Indexed as

Gene Expression Regulation, FungalHistoplasmaTranscriptomeButyratesCyclic AMPFungal ProteinsGene Expression ProfilingHyphaeTemperatureTranscription FactorsButyratesCyclic AMPFungal ProteinsTranscription Factorsfungal pathogenesishyphal developmenttranscription factors

Identifiers

PMID40928299
PMCPMC12505909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.