Evidence map›Paper›PMID 40928261›Full record

ArticleMicrobiology spectrum2025

Gina M Morgan, Ian Critchley, Nicole Cotroneo, Helio Sader, Mariana Castanheira, Rodrigo Mendes

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gina M MorganJMI Laboratories/Element Materials Technology, North Liberty, Iowa, USA.ORCID 0000-0003-2579-1657
Ian CritchleySpero Therapeutics, Cambridge, Massachusetts, USA.ORCID 0000-0003-0981-0758
Nicole CotroneoSpero Therapeutics, Cambridge, Massachusetts, USA.ORCID 0000-0002-5267-4176
Helio SaderJMI Laboratories/Element Materials Technology, North Liberty, Iowa, USA.ORCID 0000-0001-7022-6644
Mariana CastanheiraJMI Laboratories/Element Materials Technology, North Liberty, Iowa, USA.
Rodrigo MendesJMI Laboratories/Element Materials Technology, North Liberty, Iowa, USA.ORCID 0000-0002-8648-1137

Funding

Office of the Assistant Secretary for Health W81XWH-19-1-0295
6 · The paper itself

Abstract

Increasing rates of antimicrobial resistance require additional safe and effective options for managing difficult-to-treat infections. SPR206 is a next-generation polymyxin with improved

Indexed as

AcinetobacterAnti-Bacterial AgentsEnterobacteriaceaePolymyxinsPseudomonas aeruginosaDrug Resistance, Multiple, BacterialEuropeHospitalsHumansIsraelMicrobial Sensitivity TestsPseudomonas InfectionsTurkeyUnited StatesAnti-Bacterial AgentsPolymyxinscarbapenem resistanceCREDTRextensively drug-resistantmultidrug-resistantpolymyxinSPR206

Identifiers

PMID40928261
PMCPMC12502778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.