Evidence map›Paper›PMID 40928057›Full record

ReviewAutophagy2026

Microautophagy: definition, classification, and the complexity of the underlying mechanisms.

Yasuyoshi Sakai, Christian Behrends, Ana Maria Cuervo, Jayanta Debnath, Masanori Izumi, Andreas Jenny, Maurizio Molinari, Shuhei Nakamura, Masahide Oku, Marisa S Otegui and 7 more

Abstract readReview
In one paragraph

Review in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. A PI(3,5)PNature communications · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yasuyoshi SakaiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.ORCID 0000-0002-9831-3085
Christian BehrendsMunich Cluster for Systems Neurology (SyNergy), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID 0000-0002-9184-7607
Ana Maria CuervoDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, NY, USA.
Jayanta DebnathDepartment of Pathology, University of California San Francisco, San Francisco, CA, USA.
Masanori IzumiRIKEN Center for Sustainable Resource Science (CSRS), Wako, Japan.ORCID 0000-0001-5222-9163
Andreas JennyDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, NY, USA.
Maurizio MolinariInstitute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.ORCID 0000-0002-7636-5829
Shuhei NakamuraDepartment of Biochemistry, Nara Medical University, Kashihara, Nara, Japan.
Masahide OkuDepartment of Bioscience and Biotechnology, Faculty of Bioenvironmental Sciences, Kyoto University of Advanced Science, Kameoka, Kyoto, Japan.ORCID 0000-0001-5991-6281
Marisa S OteguiDepartment of Botany and Center for Quantitative Cell Imaging, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-4699-6950
Laura SantambrogioWeill Cornell Medicine, New York, NY, USA.
Han-Ming ShenFaculty of Health Sciences, Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Macau, China.ORCID 0000-0001-7369-5227
Tomohiko TaguchiLaboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.ORCID 0000-0003-0464-6370
Michael ThummDepartment of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0003-3238-4857
Takashi UshimaruCourse of Biological Science, Department of Science, Graduate School of Integrated Science and Technology, Shizuoka University, Shizuoka, Japan.
Zhiping XieSchool of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0001-5816-6159
Fulvio ReggioriDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-2652-2686

Funding

Role of Autophagy in T Cell Function and Immunosenescence (Project 3)P01AG031782 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUERVO, ANA MARIA · 2009 to 2024
$36.2M
Endolysosomal defects in secretory autophagy and microglial toxicity in FTDR01AG057462 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jayanta Debnath, Eric J Huang · 2017 to 2026
$6.9M
Autophagy in Adhesion and MetastasisR01CA126792 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jayanta Debnath · 2009 to 2026
$5.3M
DYNAMICS AND TUNING OF THE MHC II PRESENTED PEPTIDOMER01AI137198 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI SANTAMBROGIO, LAURA, STERN, LAWRENCE J. · 2018 to 2022
$4.6M
ENDOSOMAL MICROAUTOPHAGY IN DROSOPHILAR01GM119160 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JENNY, ANDREAS · 2017 to 2025
$3.9M
Autophagy as a microenvironmental regulator of tumorigenesis and resistanceR01CA188404 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BERGERS, GABRIELE, DEBNATH, JAYANTA · 2014 to 2018
$2.1M
NCI NIH HHS R01 CA126792NCI NIH HHS R01 CA188404NIAID NIH HHS R01 AI137198NIA NIH HHS P01 AG031782NIA NIH HHS R01 AG057462NIGMS NIH HHS R01 GM119160
6 · The paper itself

Abstract

Recently, rapid progress in the field of microautophagy (MI-autophagy) revealed the existence of multiple subtypes that differ in both intracellular membrane dynamics and molecular mechanisms. As a result, a single umbrella term "microautophagy" has become too vague, even creating some confusion among researchers both within and outside the field. We herein describe different subtypes of MI-autophagic processes and propose a systematic approach for naming them more accurately.

Indexed as

AutophagyMicroautophagyAnimalsEndoplasmic ReticulumHumansLysosomesAtg proteinsESCRT proteinslysosomemicroautophagyvacuole

Identifiers

PMID40928057
PMCPMC12758294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.