Evidence map›Paper›PMID 40927990›Full record

SynthesisJournal of surgical oncology2025

Superparamagnetic Iron Oxide Tracer: A Magnetic Match to Gold Standard in Melanoma Sentinel Lymph Node Biopsy-A Systematic Review and Meta-Analysis.

Kadhim Taqi, Eva Lindell Jonsson, Golpira Elmi Assadzad, Cecily Stockley, Ish Bains, Claire Temple-Oberle

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kadhim TaqiCumming School of Medicine, University of Calgary, Calgary, Canada.
Eva Lindell JonssonCumming School of Medicine, University of Calgary, Calgary, Canada.
Golpira Elmi AssadzadCumming School of Medicine, University of Calgary, Calgary, Canada.
Cecily StockleyCumming School of Medicine, University of Calgary, Calgary, Canada.ORCID https://orcid.org/0000-0001-8245-1013
Ish BainsCumming School of Medicine, University of Calgary, Calgary, Canada.
Claire Temple-OberleCumming School of Medicine, University of Calgary, Calgary, Canada.

Funding

This project was supported by a grant from the 2024 Jennifer Gardiner Award in Surgical Oncology [Grant Number: 10010377].
6 · The paper itself

Abstract

Superparamagnetic iron oxide (SPIO) tracer is a potential option for sentinel lymph node biopsy (SLNB), though its application in melanoma remains minimally explored. This systematic review evaluated the use of SPIO tracer compared to the standard approach for SLNB in melanoma. SPIO demonstrated comparable efficacy and detection rate to the gold standard, with a sensitivity of 94%. Reported adverse events included seroma and black staining. Additional research is required to determine its long-term outcomes. Trial Registration: PROSPERO: CRD 42024613648.

Indexed as

Contrast MediaMagnetic Iron Oxide NanoparticlesMelanomaSentinel Lymph Node BiopsySkin NeoplasmsHumansContrast Mediamagnetic tracermelanomasentinel lymph node biopsy (SLNB)superparamagnetic iron oxide (SPIO)

Identifiers

PMID40927990
PMCPMC12501917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.