Evidence map›Paper›PMID 40927782›Full record

ArticleEuropean journal of case reports in internal medicine2025

Brugada ECG Pattern in A Caucasian Patient with Severe Hypothyroidism.

Erminia De Cristofaro, Maria Giulia Canè, Davide Cunzi, Giorgia Prampolini, Silvia Daniela Umbertina Fedeli, Aurelio Negro

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Article in European journal of case reports in internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Erminia De CristofaroInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Maria Giulia CanèInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Davide CunziInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Giorgia PrampoliniInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Silvia Daniela Umbertina FedeliInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Aurelio NegroInternal Medicine and Hypertension Center, Sant'Anna Hospital Castelnovo ne' monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brugada syndrome (BrS) is a disorder leading to potentially life-threatening ventricular arrhythmias in patients with an apparently normal heart. It mostly affects men of Asian descent, and the prevalence varies between ethnicities. Typical ECG abnormalities with no symptoms are referred to as the Brugada pattern, and hypothyroidism is a potential trigger of this. We report on a Caucasian man with severe hypothyroidism and Brugada ECG pattern, which normalised after starting replacement therapy. The association has been previously described in only a few patients. LEARNING POINTS: Brugada syndrome (BrS) is a potentially life-threatening disease that can be easily recognized on the electrocardiogram (ECG). Typical ECG abnormalities associated with no clinical symptoms is referred to as the Brugada pattern.Many studies have underscored the association between hypothyroidism and Brugada ECG pattern, that can be reversed by a prompt initiation of replacement therapy.

Indexed as

Brugada syndromehypothyroidismischaemic heart disease

Identifiers

PMID40927782
PMCPMC12416803

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