Evidence map›Paper›PMID 40927647›Full record

ArticleCritical care explorations2025

Mean Airway Pressure-An Informative but Overlooked Indicator of Mechanical Power.

Michael G Michalik, Philip S Crooke, John J Marini

Abstract readLetter
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael G MichalikDivision of Pulmonary, Allergy, Critical Care, and Sleep, University of Minnesota, Minneapolis, MN.ORCID https://orcid.org/0000-0003-3900-0799
Philip S CrookeDepartment of Mathematics, Vanderbilt University, Nashville, TN.
John J MariniDivision of Pulmonary, Allergy, Critical Care, and Sleep, University of Minnesota, Minneapolis, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mean airway pressure, a monitored variable continuously available on the modern ventilator, is the pressure measured at the airway opening averaged over the time needed to complete the entire respiratory cycle. Mean airway pressure is well recognized to connect three key physiologic processes in mechanical ventilation: physical stretch, cardiovascular dynamics, and pulmonary gas exchange. Although other parameters currently employed in adults to determine "safe" ventilation are undoubtedly valuable for daily practice, all have limitations for continuous monitoring of ventilation hazard. The purpose of this communication is to explore the often-underappreciated link between mean airway pressure and the mechanical power (cumulative inflation energy/min) that helps determine the adverse consequences of invasive ventilation (ventilator-induced lung injury).

Indexed as

Respiration, ArtificialHumansRespiratory MechanicsVentilator-Induced Lung Injuryacute respiratory distress syndromeartificial respirationbiophysical phenomenamean airway pressuremechanical powerventilator-induced lung injury

Identifiers

PMID40927647
PMCPMC12416999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.