Evidence map›Paper›PMID 40927545›Full record

ArticleERJ open research2025

Preserved ratio impaired spirometry, dysanapsis and airflow obstruction with low forced expiratory volume in 1 s in childhood asthma.

Caroline Stridsman, Helena Backman, Lowie E G W Vanfleteren, Anna Asarnoj, Henrik Ljungberg, Anne Lindberg, Apostolos Bossios, Jon R Konradsen

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caroline StridsmanDepartment of Public Health and Clinical Medicine/The OLIN unit, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0001-6622-3838
Helena BackmanDepartment of Public Health and Clinical Medicine/The OLIN unit, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0002-0553-8067
Lowie E G W VanfleterenCOPD Center, Dept of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-4387-4096
Anna AsarnojDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Henrik LjungbergDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Anne LindbergDepartment of Public Health and Clinical Medicine/The OLIN unit, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0002-3292-7471
Apostolos BossiosDivision of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0494-2690
Jon R KonradsenDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7745-8624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Airway obstruction is a characteristic spirometric finding in asthma but the clinical significance of other abnormal spirometric patterns is less well described. We aimed to explore pre- and post-bronchodilator (BD) prevalences and clinical characteristics of preserved ratio impaired spirometry (PRISm), dysanapsis and airflow obstruction with low forced expiratory volume in 1 s (FEV Methods: We extracted specialist care data (clinical and spirometry) from the Swedish National Airway Register (n=3301, age 5-17 years). Normal spirometry was defined as FEV Results: Pre-/post-BD PRISm, dysanapsis and obstruction with low FEV Interpretation: In this paediatric asthma cohort, PRISm and dysanapsis were associated with BDRpos and they were at least as common as airflow obstruction with reduced FEV

Identifiers

PMID40927545
PMCPMC12415717

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.