ArticleERJ open research2025
Enhancing diagnostic precision: a multicentric study of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy in lymphoproliferative disorders.
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study.Respirology (Carlton, Vic.) · 2026Article
- Cryobiopsy Outperforms Fine-Needle Aspiration for Mediastinal Lymphadenopathy: A Within-Patient Diagnostic Accuracy Study and Clinical Predictors of Success.Journal of clinical medicine · 2026Article
- Comparative Efficacy of Transbronchial Needle Aspiration and Cryobiopsies in Thoracic Disorders: A Systematic Review and Meta-Analysis for Optimal Diagnostic Efficacy.Life (Basel, Switzerland) · 2026Review
- Mediastinal Ectopic Pancreas Mimicking Lymphoma with Discordant Histology and Flow Cytometry: A Diagnostic Challenge.Diagnostics (Basel, Switzerland) · 2026Article
- Approach to mediastinal cytopathology: a diagnostic overview.Mediastinum (Hong Kong, China) · 2026Review
- The evolving role of interventional pulmonology with endobronchial ultrasonography in the diagnosis of lymphoma: a narrative review.Mediastinum (Hong Kong, China) · 2026Review
- Does needle size affect the diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration for malignant lymphoma?-a narrative review.Mediastinum (Hong Kong, China) · 2026Review
- Transbronchial Mediastinal Cryobiopsy Guided by Endobronchial Ultrasound in Addition to Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Ilo-Mediastinal Lymphadenopathy Without Obvious Primary Lung Neoplastic Lesion: A Prospective Multicenter Study.Journal of clinical medicine · 2025Article
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Authors and funding
17 authors.
Funding
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Abstract
Background: The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of lymphoma has a low overall sensitivity. The lack of tissue architecture obtained by cytological needles decreases the diagnostic accuracy for diagnosis and subtyping of Methods: A multicentre retrospective observational study conducted on 40 patients who underwent both EBUS-TBNA and EBUS-TMC in the same procedure in which a definitive diagnosis of lymphoma was obtained from January 2023 to January 2024. EBUS-TBNA and EBUS-TMC were performed in the same lymph node station. Results: The overall sensitivity of EBUS-TMC was significantly higher compared to EBUS-TBNA alone and EBUS-TBNA+flow cytometry (95% Conclusions: EBUS-TMC demonstrates superior sensitivity compared to EBUS-TBNA in diagnosing and subtyping lymphoma, both in suspected new cases and recurrences. This technique reduces the need for procedural repetitions and avoids more invasive and costly interventions such as mediastinoscopy.
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Registered trials
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