Evidence map›Paper›PMID 40927518›Full record

ReviewFrontiers in oncology2025

Lung cancer associated with cystic airspaces: current status and challenges.

Linlin Wang, Yong Feng, Shiyuan Song, Jiandong Cao, Dongxu Zhang, Hong Yang, Yi Ren

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linlin WangDepartment of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Yong FengDepartment of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Shiyuan SongDepartment of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Jiandong CaoDepartment of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Dongxu ZhangDepartment of Radiology, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Hong YangDepartment of Pathology, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.
Yi RenDepartment of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer associated with cystic airspaces (LCCA) refers to primary lung cancers presenting with cystic airspaces accompanied by solid components, representing a relatively uncommon imaging and pathological phenotype. Although high-resolution imaging techniques, such as computerized tomography, are the primary diagnostic tools, early diagnosis remains challenging due to the similarity of its symptoms to other pulmonary diseases. Treatment options include surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy. However, due to the unique nature of LCCA, treatment requires a highly individualized approach. The main challenges currently faced include improving diagnostic accuracy, determining the optimal treatment strategies, and advancing the understanding of its underlying biological characteristics. Future research will focus on optimizing diagnostic techniques, developing targeted therapies for specific molecular markers, exploring the application of immunotherapies, and promoting multidisciplinary collaboration. With continuous advancements in technology and personalized treatment strategies, significant improvements in the diagnosis and treatment of LCCA are anticipated. This review summarizes the epidemiology, imaging features, pathological characteristics, pathogenesis, treatment strategies, and challenges of LCCA, and offers perspectives on future research directions.

Indexed as

challengesdiagnosisimaging phenotypelung cancer associated with cystic airspaces (LCCA)pathology

Identifiers

PMID40927518
PMCPMC12414957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.