Evidence map›Paper›PMID 40927517›Full record

ArticleFrontiers in oncology2025

A compilation of 13 patients with metastatic colorectal cancer and concomitant

Jigisha Srivastav, Morgan E Lehman, Joni K Evans, Ravi Paluri, Caio Max Sao Pedro Rocha Lima

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Detection ofOncology research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jigisha SrivastavDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Morgan E LehmanDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Joni K EvansDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Ravi PaluriDepartment of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Caio Max Sao Pedro Rocha LimaDepartment of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Metastatic colorectal cancer (mCRC) exhibits significant heterogeneity in molecular profiles, influencing treatment response and patient outcomes. Mutations in v-raf murine sarcoma viral oncogene homolog B1 ( Methods: Below we present a retrospective study on 13 patients with concomitant Results: Thirteen mCRC patients, 61.5% male, with a median age of diagnosis of 64.4 years had concomitant Discussion: This study adds more insight to the limited existing data regarding rare mCRC cases with concomitant

Indexed as

BRAF mutationclinical-pathological featurescolorectal cancerconcurrent RAS/BRAF variantsKRAS mutationNRAS mutationRAS family mutation

Identifiers

PMID40927517
PMCPMC12414759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.