Evidence map›Paper›PMID 40927428›Full record

ArticleAmerican heart journal plus : cardiology research and practice2025

Evaluation of lipid profile and high sensitive C reactive protein levels among cigarette smokers in East Gojjam, Ethiopia.

Gelagey Baye, Bayu Wondmneh, Baye Ashenef, Mohammed Jemal, Temesgen Baylie, Enyew Fenta Mengistu, Adane Adugna

Abstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gelagey BayeDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Bayu WondmnehDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Baye AshenefDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Mohammed JemalDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Temesgen BaylieDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Enyew Fenta MengistuDepartment of Biomedical Science, Debre Markos University, Debre Markos, Ethiopia.
Adane AdugnaDepartment of Medical Laboratory Science, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cigarette smoking is a well-recognized independent risk factor for numerous cardiovascular disorders and contributes to the increasing morbidity and mortality associated with chronic heart diseases (CHD). This study aimed to evaluate how cigarette smoking affects lipid metabolism and inflammatory processes, along with other related mechanisms, in order to better understand the potential cardiovascular risks faced by smokers. Objectives: To evaluate and compare the serum lipid profile and high-sensitivity C-reactive protein levels between cigarette smokers and non-smokers. Methods: A hospital-based comparative cross-sectional study was conducted from December 2023 to May 2024 in East Gojjam, Ethiopia. The study included 150 cigarette smokers and 150 non-smokers. Independent Result: The mean serum levels of total cholesterol, low-density lipoprotein, triglycerides, high-density lipoprotein, and high-sensitivity C-reactive protein in cigarette smokers were 178.46 ± 76.34 mg/dL, 112.36 ± 73.58 mg/dL, 138.80 ± 61.88 mg/dL, 38.33 ± 7.99 mg/dL, and 6.26 ± 5.53 mg/L, respectively. These values were significantly different from those of non-smokers ( Conclusion: Serum mean levels of total cholesterol, low-density lipoprotein, triglycerides, and high-sensitivity C-reactive protein were significantly higher in cigarette smokers compared to non-smokers. In contrast, the mean serum level of high-density lipoprotein was significantly lower in smokers. These changes-elevated TC, LDL-C, TG, and hsCRP, along with decreased HDL-C-may increase the risk of cardiovascular diseases among cigarette smokers.

Indexed as

BiomarkersBlood lipidscardiovascular diseasesC - reactive proteinInflammation mediatorsLipid metabolismTobacco smoking

Identifiers

PMID40927428
PMCPMC12414901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.