Evidence map›Paper›PMID 40927420›Full record

ArticleFrontiers in neuroscience2025

Serotonin 5-HT

Sandy C Simões, Livia N Amorim, Yasmim A Serra, Camila S Abreu, Maria Clara E Santana, João P C Leite, Carla M Kaneto, Roberta C A Costa, Kaio R Ferreira, Isabelle C S de Oliveira and 5 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sandy C Simões *Department of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Livia N Amorim *Department of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Yasmim A SerraDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Camila S AbreuDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Maria Clara E SantanaDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
João P C LeiteDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Carla M KanetoDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Roberta C A CostaDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Kaio R FerreiraDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Isabelle C S de OliveiraDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Alexandre J Oliveira-LimaDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Agnieszka SulimaDepartment of Psychiatry and Human Behavior, Center for Innovation and Discovery in Addictions, University of Mississippi Medical Center, Jackson, MS, United States.
Kenner C RiceDrug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Eduardo A V MarinhoDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Lais F BerroDepartment of Health Sciences, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Studies suggest that serotonin (5-HT) plays an important role in alcohol use disorder (AUD). While several receptor subtypes modulate the role of 5-HT in AUD, evidence suggests that 5-HT Methods: Animals had intermittent access to alcohol (10% v/v) in a two-bottle choice procedure for 30 days (acquisition), and were then submitted to alcohol re-exposure sessions after periods of abstinence. Vehicle, the 5-HT Results: Our findings show that combined treatment with 5-HT Discussion: Our findings suggest that 5-HT

Indexed as

5-HT2A5-HT2Calcoholmiceserotonintwo-bottle choice

Identifiers

PMID40927420
PMCPMC12414994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.