Observational studyFrontiers in endocrinology2025
Association of inflammatory index with the severity of disease in patients with acute myocarditis: A retrospective observational study.
Observational study in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Systemic Inflammation Response Index Is Associated with the Presence and Extent of Late Gadolinium Enhancement in Acute Myocarditis.Journal of clinical medicine · 2026Article
- Peripheral blood cells and immune checkpoint inhibitor-associated myocarditis: a retrospective clinical study with pharmacovigilance and single-cell analysis.Frontiers in immunology · 2026Article
- Short-term outcome and prognostic factors in acute fulminant myocarditis with acute kidney injury patients.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This research aimed to investigate the association between neutrophil-percentage-to-albumin ratio (NPAR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI) with disease severity in patients diagnosed with acute myocarditis. Methods: A total of 185 patients were diagnosed with acute myocarditis at the First Hospital of Jilin University between 2018 and 2024. The related values of NPAR, SII, SIRI, and AISI were computed based on the pertinent blood indices that were acquired within 12 hours of admission. The best cut-off values for NPAR, SII, SIRI, and AISI, as well as their associated sensitivity and specificity, were determined using ROC curve analysis in order to assess their predictive usefulness for poor prognosis upon admission. Results: Patients with fulminant myocarditis exhibited significantly higher NPAR, SII, SIRI, and AISI values compared to those with mild myocarditis. Spearman correlation analysis revealed significant associations between these inflammatory indices and NYHA scores at admission (r = 0.370, 0.296, 0.284, and 0.246, respectively; Conclusions: Our study demonstrated that inflammatory biomarkers - NPAR, SII, SIRI, and AISI - show associations with the severity of acute myocarditis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.