Evidence map›Paper›PMID 40927167›Full record

ArticleFrontiers in veterinary science2025

Ameliorative effects of

Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Olufunke Onaadepo, Felix Nnaemeka Ugwu, Patrick Maduabuchi Aja

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emmanuel Orire IkuomolaDepartment of Physiology, Faculty of Biomedical Sciences, Kampala International University Western Campus, Bushenyi, Uganda.
Daniel Udofia OwuDepartment of Physiology, Faculty of Biomedical Sciences, Kampala International University Western Campus, Bushenyi, Uganda.
Victor Otu OkaDepartment of Physiology, Faculty of Biomedical Sciences, Kampala International University Western Campus, Bushenyi, Uganda.
Olufunke OnaadepoDepartment of Physiology, Faculty of Biomedical Sciences, Kampala International University Western Campus, Bushenyi, Uganda.
Felix Nnaemeka UgwuDepartment of Physiology, Faculty of Biomedical Sciences, Kampala International University, Kampala, Tanzania.
Patrick Maduabuchi AjaDepartment of Biochemistry, Faculty of Biomedical Sciences, Kampala International University Western Campus, Bushenyi, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Male infertility is a global health issue, with pharmaceutical agents such as cimetidine contributing significantly to gonadotoxicity through antiandrogenic and oxidative mechanisms. The search for natural protective agents has highlighted Objectives: This study evaluated the protective effects of Methods: Thirty-five rats were divided into seven groups: control, cimetidine (120 mg/kg), ethanol extract (200 mg/kg), and cimetidine + fractions (aqueous, butanol, and hexane). After 8 weeks oral administration of extracts/fractions, sperm parameters, serum hormones (LH, FSH, and testosterone), oxidative stress markers (catalase, SOD, and MDA), and histopathology were assessed. Results: Cimetidine significantly reduce follicle stimulating hormone (FSH), luteinizing hormone (LH) and testosterone levels ( Conclusion:

Indexed as

Brassica oleraceacimetidinecollard greenshormonal regulationoxidative stress

Identifiers

PMID40927167
PMCPMC12415695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.