ArticleApplied biosafety : journal of the American Biological Safety Association2025
A Review of Accidental Aerosol Generation in Laboratories and Laboratory-associated Infections.
Article in Applied biosafety : journal of the American Biological Safety Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Virology laboratory biohazards: infectious MS2 aerosols emitted from common procedures and accidental laboratory scenarios in a controlled chamber study.Applied and environmental microbiology · 2026Article
- An 8-step procedure-specific risk framework enables reproducible biosafety level assignment beyond agent-based classification.Frontiers in bioengineering and biotechnology · 2026Article
- Successful Inactivation of High-Consequence Pathogens in PrimeStore Molecular Transport Media.Viruses · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Laboratory-acquired infections (LAIs) from exposure to infectious biological pathogens during laboratory operations present ongoing challenges despite modern biosafety measures. Notably, LAIs attributed to inhaling infectious aerosols continue to occur. Objective: This review aims to enhance understanding of the risks of LAIs associated with infectious aerosols. The first objective of this review is to summarize studies that have characterized the potential for accidental aerosol generation in biological laboratories and to synthesize these findings. The second objective is to examine past LAI incidents involving infectious aerosol exposure to identify knowledge gaps. Methods: A literature review using PubMed and Google Scholar databases with relevant keywords was performed. The results were screened to identify studies that reported LAIs related to aerosol exposures. Thirty-eight articles pertaining to LAIs involving infectious aerosol exposures from an initial pool of 63 articles were identified. Discussion and Conclusions: This review underscores the need for comprehensive safety protocols to mitigate risks associated with LAIs due to aerosol generation. It identifies critical gaps in understanding aerosol dynamics, such as particle size distribution and the influence of laboratory automation. The review also highlights the inadequacy of current LAI reporting practices, advocating for improved documentation and standardized methods to enhance biosafety in laboratory settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.