ArticleClinical ophthalmology (Auckland, N.Z.)2025
Femtosecond-Laser-Assisted Liquid-Interface vs Vacuum-Trephine Keratoplasty: A Comparison of 2 Different Techniques - Retrospective Data Analysis.
Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Femtosecond Laser-Assisted Keratoplasty: A Narrative Review of Technological Evolution, Clinical Evidence, Implementation and Future Directions.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
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7 authors.
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Abstract
Purpose: To compare postoperative astigmatism and visual acuity (VA) outcomes in patients undergoing penetrating keratoplasty (PK) using a liquid-interface femtosecond laser (LI-fs) trephination and a conventional vacuum-trephine (VT) technique. Methods: Our single-center, retrospective data analysis included 121 eyes (121 patients) treated between April 2014 and November 2022. Patients received PK either with a LI-fs or a VT system. Pre- and postoperative topography (K-values), refraction (cylinder) and visual acuity (VA) were measured up to 18 months after surgery. Data were analyzed by descriptive statistics, ANCOVA, and paired t-tests within each group. Results: Preoperative and postoperative astigmatism were similar between the two techniques (LI-fs: 5.4 ± 3.4 D pre-OP vs 6.7 ± 4.2 D post-OP; VT group: 5.8 ± 4.8 D vs 6.7 ± 3.8D). An ANCOVA adjusting for baseline astigmatism (=∆K in topography imaging) revealed no statistically significant difference between groups (estimate [95% CI]: -0.79 [-2.73; 1.15], p = 0.42). Within-group changes in astigmatism were also not significant. For VA, a paired Conclusion: Despite the characteristics of LI-fs in maintaining corneal curvature, LI-fs and conventional VT generated comparable outcomes in terms of post-OP astigmatism. The results underscore the need for further research with larger cohorts to clarify any potential advantages of the LI-fs in reducing surgically-induced astigmatism.
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