ArticleReviews in cardiovascular medicine2025
Serum Albumin is Linearly and Negatively Associated With the Risk of All-cause and Cardiovascular Death in Coronary Heart Disease Patients.
Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Prognostic Value of the Uric Acid-to-Albumin Ratio in Patients Undergoing Successful Percutaneous Coronary Intervention for Chronic Total Occlusion.Journal of cardiovascular development and disease · 2026Article
- Serum free fatty acids and progression of coronary artery calcification: sex specific findings from a large U.S. cohort study.BMC cardiovascular disorders · 2026Article
- Higher Neutrophil-to-Albumin Ratio Is Associated with Greater Coronary Atherosclerotic Burden According to the Gensini Score in an Angiography-Referred Population.Diagnostics (Basel, Switzerland) · 2026Article
- Serum Albumin Level Predicts Systemic Arterial Stiffening Mediated Partially by Change in Lean Body Mass: A Retrospective Cohort Study in General Japanese Population.Vascular health and risk management · 2026Article
- Association between impaired peripheral thyroid hormone sensitivity and coronary heart disease in type 2 diabetes: the potential mediating role of albumin.Frontiers in endocrinology · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite advances in treatment and the potential role of serum albumin as a prognostic biomarker, the mortality rate of individuals with coronary heart disease (CHD) continues to increase. Thus, this study aimed to assess the relationship between serum albumin levels and the risk of all-cause mortality and cardiovascular death in individuals with CHD. Methods: This large-scale retrospective cohort study included 1556 participants diagnosed with CHD from the National Health and Nutrition Examination Survey spanning 1999 to 2015. We conducted multivariate Cox regression, subgroup and sensitivity analyses, and restricted cubic spline (RCS) plots to examine the link between serum albumin levels and all-cause mortality and cardiovascular death. Results: After gradually adjusting the confounding variables, serum albumin consistently demonstrated a strong link to increased overall and cardiovascular-related mortality risk when employed as a continuous variable (hazard ratio [HR]: 0.938, 95% confidence interval [CI]: 0.912-0.964; Conclusions: The serum albumin levels in individuals with CHD were inversely and linearly related to all-cause mortality and cardiovascular death risk.
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