Evidence map›Paper›PMID 40927105›Full record

ArticleReviews in cardiovascular medicine2025

Rapid Atrial Pacing After TAVI for Pacemaker Prediction.

Leonidas Koliastasis, Ioannis Doundoulakis, Dimitrios Tsiachris, Luigi Pannone, Ioannis Skalidis, Quentin de Hemptinne, Panagiotis Xaplanteris, Konstantinos Toutouzas, Carlo de Asmundis

Registry-linked trialAbstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06189976 (Rapid Atrial Pacing After TAVI as a Predictor of Permanent Pacemaker Implantation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06189976 narecruitingnot on this map

Rapid Atrial Pacing After TAVI as a Predictor of Permanent Pacemaker Implantation

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2024 to 2025Enrolled400ConditionsAortic Valve Disease, Transcatheter Aortic Valve Implantation, TAVIArmsRapid atrial pacing
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leonidas KoliastasisDepartment of Cardiology, Université Libre de Bruxelles (ULB), Centre Hospitalier Universitaire Saint-Pierre, 1000 Brussels, Belgium.ORCID https://orcid.org/0000-0002-7966-9174
Ioannis DoundoulakisHeart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, 1090 Brussels, Belgium.ORCID https://orcid.org/0000-0003-2184-3296
Dimitrios TsiachrisUnit of Structural Heart Disease and Valvular Disease, First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration Hospital, 11527 Athens, Greece.
Luigi PannoneHeart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, 1090 Brussels, Belgium.
Ioannis SkalidisService de Cardiologie, Institut Cardiovasculaire Paris Sud, 91300 Massy, France.
Quentin de HemptinneDepartment of Cardiology, Université Libre de Bruxelles (ULB), Centre Hospitalier Universitaire Saint-Pierre, 1000 Brussels, Belgium.
Panagiotis XaplanterisDepartment of Cardiology, Université Libre de Bruxelles (ULB), Centre Hospitalier Universitaire Saint-Pierre, 1000 Brussels, Belgium.
Konstantinos ToutouzasUnit of Structural Heart Disease and Valvular Disease, First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration Hospital, 11527 Athens, Greece.
Carlo de AsmundisHeart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, 1090 Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite continued advancements in transcatheter aortic valve implantation (TAVI) techniques, the incidence of permanent pacemaker implantation (PPI) remains substantial. Established predictors of PPI include advanced age, pre-existing electrocardiographic conduction abnormalities, prosthetic valve type, implantation depth, and anatomical parameters, such as membranous septum length, which are currently under active investigation. In routine clinical practice, the management strategy often involves the temporary placement of a transvenous pacemaker lead, followed by a period of observation. While widely implemented, this approach introduces clinical uncertainty and may contribute to prolonged hospitalization, particularly given the not infrequent occurrence of delayed high-degree atrioventricular (AV) block. A novel diagnostic method emerging from electrophysiological evaluation is rapid atrial pacing performed post-TAVI, which aims to assess susceptibility to Wenckebach-type AV block. Two observational studies have evaluated this technique, utilizing an upper pacing threshold of 120 beats per minute as a cutoff to identify patients at risk of requiring permanent pacing. Moreover, this method is cost-effective, technically straightforward, and time-efficient; preliminary findings suggest this technique possesses a high negative predictive value. However, additional prospective data are required to validate the clinical utility of this technique and inform the development of standardized implementation. An upcoming clinical study (NCT06189976) is anticipated to provide valuable insights.

Indexed as

pacemakerpredictorsrapid atrial pacingTAVITAVR

Identifiers

PMID40927105
PMCPMC12415755

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.