Evidence map›Paper›PMID 40927075›Full record

ReviewReviews in cardiovascular medicine2025

Advances and Prospects in the Diagnosis and Treatment of Blood Culture-Negative Infective Endocarditis.

Wei Ji, Zhihuang Zhao, Xinjun Lin, Wanjun Huang, Qidong Chen, Yuwei Chen, Liyong Shi, Chaoxiang Xu, Xiaoyang Chen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. ASM case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei JiThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0000-0003-4546-4135
Zhihuang ZhaoThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0006-0539-0468
Xinjun LinThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0001-6329-8313
Wanjun HuangThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0002-2324-9653
Qidong ChenThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0009-1772-5642
Yuwei ChenThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0001-0180-8824
Liyong ShiThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0000-0003-1374-1193
Chaoxiang XuThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0009-0002-6331-2629
Xiaoyang ChenThe Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.ORCID https://orcid.org/0000-0002-2533-1928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood culture-negative infective endocarditis (BCNE) constitutes an important subtype of infective endocarditis. Despite the rarity of BCNE, this subtype poses a significant diagnostic challenge and promotes a high mortality rate. Recent advances in diagnostic modalities have facilitated the rapid identification of BCNE. Moreover, empiric diagnostic and therapeutic approaches, supported by intensive and rigorous epidemiological and observational investigations, have yielded positive results. There is a growing inclination in clinical management toward early surgical interventions while rigorously assessing surgical risks, complications, and anticipated benefits. This review examines the epidemiology, microbiological data, and diagnoses of medical and surgical BCNE in contemporary practices.

Indexed as

BCNEdiagnoseendocarditisetiologytreatment

Identifiers

PMID40927075
PMCPMC12415764

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.