Evidence map›Paper›PMID 40927059›Full record

ArticleIJID regions2025

Public health response to immunodeficiency-related vaccine-derived poliovirus during a poliovirus outbreak in the Philippines: a case report.

Krizia Joy A Co, Paul Sherwin O Tarnate, Mary Anne R Castor, Anna Lisa T Ong-Lim

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Krizia Joy A CoDivision of Infectious and Tropical Diseases in Pediatrics, Department of Pediatrics, College of Medicine - Philippine General Hospital, University of the Philippines, Manila, Philippines.
Paul Sherwin O TarnateDivision of Infectious and Tropical Diseases in Pediatrics, Department of Pediatrics, College of Medicine - Philippine General Hospital, University of the Philippines, Manila, Philippines.
Mary Anne R CastorDivision of Allergy and Immunology, Department of Pediatrics, College of Medicine - Philippine General Hospital, University of the Philippines, Manila, Philippines.
Anna Lisa T Ong-LimDivision of Infectious and Tropical Diseases in Pediatrics, Department of Pediatrics, College of Medicine - Philippine General Hospital, University of the Philippines, Manila, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunodeficiency-related vaccine-derived poliovirus (iVDPV) was detected in the stool of a 5-year-old male patient with combined immunodeficiency. The patient presented in August 2019 with chronic diarrhea, fever, and generalized weakness. This case was identified concurrently with the 2019-2020 poliovirus outbreak in the Philippines. Antiviral therapy with pocapavir and remdesivir was administered but was unsuccessful in iVDPV clearance. The patient remained a chronic iVDPV excretor until his death in 2023.

Indexed as

Case reportCombined immunodeficiencyImmunodeficiency-related vaccine-derived poliovirusPocapavirPoliovirusRemdesivir

Identifiers

PMID40927059
PMCPMC12415075

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.