Evidence map›Paper›PMID 40927047›Full record

ArticleFood science & nutrition2025

Exploring the In Vitro Anti-Inflammatory Effect of Citrus Fruit Hesperidin Supplementation.

Syed Yaseen Raza Zaidi, Aftab Ahmed, Gaurav Sanghvi, R Roopashree, Aditya Kashyap, Nameer Khairullah Mohammed, Bushra Niaz, Farhan Saeed, Faiza Jamil, Muhammad Nadeem Akhter and 2 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Syed Yaseen Raza ZaidiDepartment of Nutritional Sciences Government College University Faisalabad Pakistan.
Aftab AhmedDepartment of Nutritional Sciences Government College University Faisalabad Pakistan.
Gaurav SanghviMarwadi University Research Center, Department of Microbiology, Faculty of Science Marwadi University Rajkot Gujarat India.
R RoopashreeDepartment of Chemistry and Biochemistry, School of Sciences JAIN (Deemed to Be University) Bangalore Karnataka India.
Aditya KashyapCentre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology Chitkara University Rajpura Punjab India.
Nameer Khairullah MohammedDepartment of Food Science, Faculty of Agriculture Tikrit University Tikrit Iraq.ORCID https://orcid.org/0000-0002-9202-0281
Bushra NiazDepartment of Food Science Government College University Faisalabad Pakistan.
Farhan SaeedDepartment of Food Science Government College University Faisalabad Pakistan.ORCID https://orcid.org/0000-0001-5340-4015
Faiza JamilDepartment of Food Science Government College University Faisalabad Pakistan.
Muhammad Nadeem AkhterUniversity Institute of Diet and Nutritional Sciences University of Lahore Lahore Pakistan.ORCID https://orcid.org/0000-0002-8610-2686
Muhammad AfzaalDepartment of Food Science Government College University Faisalabad Pakistan.ORCID https://orcid.org/0000-0001-9047-9075
Catherine Tamale NdagireDepartment of Food Innovation and Nutrition Mountains of the Moon University Fort Portal Uganda.ORCID https://orcid.org/0000-0002-2695-8466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to assess the anti-inflammatory effect of hesperidin. The research was conducted by optimizing the hesperidin extraction process from citrus peel powder, followed by characterization and nutrition profiling of citrus peel hesperidin extract. Citrus peel was collected from the local market and dried in a hot air oven. Then it was ground in a grinder to make powder. Then, the powder was extracted first with petroleum ether and then with methanol inside a Soxhlet apparatus. Then, the methanolic extract was filtered and subjected to evaporation in a rotary evaporator. Hesperidin was precipitated and purified with the help of acetic acid and dimethylformamide. The anti-inflammatory and antioxidant perspective of hesperidin was assessed through NO

Indexed as

anti‐inflammatoryantioxidantcitrus fruithesperidin

Identifiers

PMID40927047
PMCPMC12414805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.