ArticleOrthopedic reviews2025
Comparative Efficacy of Platelet-Rich Plasma and Corticosteroid Injections for Rotator Cuff Injury Management: A Systematic Review and Meta-Analysis.
Article in Orthopedic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Platelet-rich plasma provides modest but durable functional benefit over corticosteroid for rotator cuff tendinopathy: A systematic review and meta-analysis of randomized controlled trials.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Comparative Outcome Analysis of Leukocyte-Rich Platelet-rich Plasma, Leukocyte-Poor Platelet-rich Plasma, Injectable Platelet-rich Fibrin and Corticosteroid Injections in Periarthritis of the Shoulder: A Double-Blinded, Four-Arm Randomized Controlled Trial.Journal of orthopaedic case reports · 2026Article
- Rotator Cuff Disorders: Practical Recommendations for Conservative Management Based on the Literature.Medicina (Kaunas, Lithuania) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Rotator cuff injuries are very common in the athletic population and both corticosteroid injections and platelets enriched plasma (PRP) are common management options used in clinical practice yet there aren't any recent systematic reviews that compare between the two, thus, this study aims to provide a high-quality systematic review of the clinical trials and the experimentation found in the literature as of yet to guide practitioners in choosing between these two management options. Methods: This systematic review was conducted in accordance to PRISMA guidelines and was registered in PROSPERO (CRD4202461663). A comprehensive search was done in the following databases MEDLINE, Web of Science, Google Scholar. The included studies were comparing Platelet Rich-Plasma with Corticosteroid injections for rotator cuff injuries for Adult patients that struggled with the injury for more than three months. The measurements that were used to determine the outcomes were: pain (VAS score) and functional scores (e.g Constant-Murley, ASES, SST). Results: Pain reduction (VAS score) PRP showed to be somewhat better in the short term but had similar scores to corticosteroids on the remaining time marks, with the difference between them being insignificant, also, PRP showed to be more effective than Corticosteroids in improving function, particularly as time went on, the difference became more apparent (at 3-6 weeks, the mean difference was -3.97, after 24 weeks, it became 9.85 Constant-Murley). Conclusion: When comparing between corticosteroids and PRP, there is no significant difference between them regarding pain reduction, yet, PRP has proven its effectiveness over the long-term for functional improvement, and which means that it could see more clinical use provided that it is cost-effective, yet more research is required to reach a final judgment and thorough evaluation due to the heterogeneity found in the studies.
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