Evidence map›Paper›PMID 40926922›Full record

ArticleCureus2025

Unexpected CA 19-9 Elevation in a Patient With a Splenic Epithelial Cyst: A Diagnostic Challenge.

Mohammed A Alsuhaimi, Mohmmed A AlHewishel, May S AlKhaldi, Abdurahman S AlSumaihi, Khaled S Albahout

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammed A AlsuhaimiSurgery, Dammam Medical Complex, Dammam, SAU.
Mohmmed A AlHewishelGeneral Surgery, Dammam Medical Complex, Dammam, SAU.
May S AlKhaldiGeneral Surgery, Dammam Medical Complex, Dammam, SAU.
Abdurahman S AlSumaihiGeneral Surgery, Dammam Medical Complex, Dammam, SAU.
Khaled S AlbahoutGeneral Surgery, King Fahad University Hospital, Khobar, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic epithelial cysts are rare, benign lesions often discovered incidentally. Although typically asymptomatic, they can sometimes present with elevated tumor markers, such as CA 19-9, raising concerns for malignancy. We report the case of a 44-year-old woman who was found to have elevated liver enzymes and CA 19-9 levels. Imaging revealed a unilocular splenic cyst. Laparoscopic splenectomy was performed, and histopathology confirmed a benign epithelial cyst. Postoperatively, CA 19-9 levels declined significantly. This case highlights the importance of considering benign etiologies in patients with elevated tumor markers and emphasizes the role of imaging and surgical pathology in establishing a diagnosis.

Indexed as

benign splenic lesionca 19-9laparoscopic splenectomynon-malignant ca 19-9 elevationsplenic epithelial cyst

Identifiers

PMID40926922
PMCPMC12416856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.